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Details on Person The histidyl-tRNA synthetase domain in the C-terminal region...
| Class:Id | Summation:9633767 |
|---|---|
| _displayName | The histidyl-tRNA synthetase domain in the C-terminal region... |
| _timestamp | 2019-08-13 02:00:09 |
| created | [InstanceEdit:9633796] May, Bruce, 2018-12-30 |
| modified | [InstanceEdit:9635234] May, Bruce, 2019-01-19 [InstanceEdit:9635240] May, Bruce, 2019-01-19 [InstanceEdit:9635280] May, Bruce, 2019-01-20 [InstanceEdit:9635320] May, Bruce, 2019-01-27 [InstanceEdit:9645380] May, Bruce, 2019-05-11 [InstanceEdit:9658335] May, Bruce, 2019-08-13 |
| text | The histidyl-tRNA synthetase domain in the C-terminal region of Eif2ak4 (Gcn2) binds uncharged tRNA (inferred from yeast homologs). Gcn1 and Eif2ak4 interact with translating ribosomes (Roffe et al. 2013) and with each other (Cambiaghi et al. 2014), though the interaction between mouse Eif2ak4 and ribosomes is not as stable as the interaction between yeast GCN2 and ribosomes. The interaction between Gcn1 and Eif2ak4 is required for activation of Atf4 and Chop by Eif2ak4 (Cambiaghi et al. 2014). |
| (summation) | [Reaction:9633481] Eif2ak4 binds tRNA [Mus musculus] |
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No pathways have been reviewed or authored by The histidyl-tRNA synthetase domain in the C-terminal region... (9633767)
