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Details on Person Eif2ak4 binds tRNA

Class:Id	Reaction:9633481
_displayName	Eif2ak4 binds tRNA
_doRelease	TRUE
_timestamp	2019-11-20 13:51:31
authored	[InstanceEdit:9633461] May, Bruce, 2018-12-28
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9633466] May, Bruce, 2018-12-29
edited	[InstanceEdit:9633461] May, Bruce, 2018-12-28
inferredFrom	[Reaction:9633467] GCN2 binds tRNA [Saccharomyces cerevisiae]
input	[Complex:9633499] Eif2ak4:Gcn1:80S ribosome:mRNA [cytosol] [Mus musculus] [GenomeEncodedEntity:9633589] tRNA [cytosol] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:9633736] Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2 [LiteratureReference:9633782] IMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowth [LiteratureReference:9635219] Crystal structures of GCN2 protein kinase C-terminal domains suggest regulatory differences in yeast and mammals [LiteratureReference:9635304] Re-examination of Dietary Amino Acid Sensing Reveals a GCN2-Independent Mechanism
modified	[InstanceEdit:9633856] May, Bruce, 2018-12-30 [InstanceEdit:9635234] May, Bruce, 2019-01-19 [InstanceEdit:9635240] May, Bruce, 2019-01-19 [InstanceEdit:9635280] May, Bruce, 2019-01-20 [InstanceEdit:9635319] May, Bruce, 2019-01-26 [InstanceEdit:9635320] May, Bruce, 2019-01-27 [InstanceEdit:9645380] May, Bruce, 2019-05-11 [InstanceEdit:9658335] May, Bruce, 2019-08-13 [InstanceEdit:9661248] May, Bruce, 2019-09-15 [InstanceEdit:9668176] May, Bruce, 2019-11-20 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Eif2ak4 binds tRNA
output	[Complex:9633566] tRNA:Eif2ak4:Gcn1:80S ribosome:mRNA [cytosol] [Mus musculus]
releaseDate	2019-12-10
reviewed	[InstanceEdit:9661246] Bruhat, Alain, 2019-09-15 [InstanceEdit:9668172] Staschke, Kirk A, 2019-11-20
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9633636] R-MMU-9633481.3
summation	[Summation:9633767] The histidyl-tRNA synthetase domain in the C-terminal region...
(inferredFrom)	[Reaction:9633005] EIF2AK4 (GCN2) binds tRNA [Homo sapiens]
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No pathways have been reviewed or authored by Eif2ak4 binds tRNA (9633481)