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Details on Person p16INK4A W110* [cytosol]
Class:Id EntityWithAccessionedSequence:9632585
_displayName p16INK4A W110* [cytosol]
_timestamp 2019-06-13 15:35:12
compartment [Compartment:70101] cytosol
created [InstanceEdit:9632589] Orlic-Milacic, Marija, 2018-12-19
crossReference [DatabaseIdentifier:9632641] COSMIC:COSM13783 [DatabaseIdentifier:9632648] COSMIC:COSV58682976 [DatabaseIdentifier:9632650] COSMIC:COSV58682827
disease [Disease:1500689] cancer [Disease:1614289] melanoma [Disease:2328001] skin squamous cell carcinoma [Disease:1655484] kidney cancer [Disease:1248679] head and neck squamous cell carcinoma [Disease:2328083] larynx cancer [Disease:6802256] thyroid carcinoma [Disease:9632204] Barrett's esophagus [Disease:1996318] astrocytoma [Disease:2327989] bile duct carcinoma [Disease:9632339] esophagus adenocarcinoma [Disease:9630862] esophagus squamous cell carcinoma [Disease:1500699] lung cancer [Disease:1981182] lung squamous cell carcinoma [Disease:9630864] pancreatic ductal adenocarcinoma [Disease:9632619] sebaceous carcinoma [Disease:1500687] stomach cancer [Disease:1655468] thymus cancer [Disease:1493885] bladder carcinoma [Disease:9630843] oral squamous cell carcinoma [Disease:2317476] acute lymphocytic leukemia [Disease:2317358] endometrial cancer [Disease:1247848] non-small cell lung carcinoma [Disease:9632612] fibrous histiocytoma [Disease:9630850] pharynx squamous cell carcinoma [Disease:9632101] vulva squamous cell carcinoma [Disease:9632647] trachea squamous cell carcinoma
endCoordinate 109
hasModifiedResidue [NonsenseMutation:9649383] Nonsense mutation at L-tryptophan 110
literatureReference [LiteratureReference:9632578] CDKN2A/p16 is inactivated in most melanoma cell lines
modified [InstanceEdit:9632643] Orlic-Milacic, Marija, 2018-12-20 [InstanceEdit:9632651] Orlic-Milacic, Marija, 2018-12-20 [InstanceEdit:9645193] Orlic-Milacic, Marija, 2019-05-06 [InstanceEdit:9648380] Orlic-Milacic, Marija, 2019-06-06 [InstanceEdit:9649386] Orlic-Milacic, Marija, 2019-06-13
name p16INK4A W110* p16INK4A W110TER p16INK4A Trp110TER p16INK4A Trp110* CDKN2A W110TER CDKN2A Trp110TER CDKN2A W110* CDKN2A Trp110*
referenceEntity [ReferenceGeneProduct:87039] UniProt:P42771 CDKN2A [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9632592] R-HSA-9632585.2
startCoordinate 1
(hasMember) [CandidateSet:9630804] p16INK4A LoF mutants (CDK4/6) [cytosol] [Homo sapiens]
(updatedInstance) [_UpdateTracker:9900644] Update Tracker - [EntityWithAccessionedSequence:9632585] p16INK4A W110* [cytosol] - v70:[addHasModifiedResidue]
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Pathways
No pathways have been reviewed or authored by p16INK4A W110* [cytosol] (9632585)