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Details on Person p16INK4A D84N [cytosol]

Class:Id	EntityWithAccessionedSequence:9632483
_displayName	p16INK4A D84N [cytosol]
_timestamp	2019-05-06 20:08:12
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9632490] Orlic-Milacic, Marija, 2018-12-18
disease	[Disease:1500689] cancer [Disease:8853117] lung adenocarcinoma [Disease:2327989] bile duct carcinoma [Disease:9630851] gallbladder adenocarcinoma [Disease:2318519] medulloblastoma [Disease:9632339] esophagus adenocarcinoma [Disease:1981182] lung squamous cell carcinoma [Disease:9630862] esophagus squamous cell carcinoma [Disease:1500575] ovarian cancer [Disease:9630864] pancreatic ductal adenocarcinoma [Disease:2328001] skin squamous cell carcinoma [Disease:1614289] melanoma [Disease:1248679] head and neck squamous cell carcinoma
endCoordinate	156
hasModifiedResidue	[ReplacedResidue:9632484] L-aspartic acid 84 replaced with L-asparagine
literatureReference	[LiteratureReference:9632507] Functional evaluation of tumour-specific variants of p16INK4a/CDKN2A: correlation with protein structure information
modified	[InstanceEdit:9632506] Orlic-Milacic, Marija, 2018-12-19 [InstanceEdit:9645190] Orlic-Milacic, Marija, 2019-05-06
name	p16INK4A D84N p16INK4A Asp84Asn CDKN2A D84N CDKN2A Asp84Asn
referenceEntity	[ReferenceGeneProduct:87039] UniProt:P42771 CDKN2A [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9632492] R-HSA-9632483.1
startCoordinate	1
(hasMember)	[CandidateSet:9630804] p16INK4A LoF mutants (CDK4/6) [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by p16INK4A D84N [cytosol] (9632483)