Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person PRMT1 methylates ESRs

Class:IdReaction:9632182
_displayNamePRMT1 methylates ESRs
_doReleaseTRUE
_timestamp2019-05-02 03:07:19
authored[InstanceEdit:9632125] Rothfels, Karen, 2018-12-14
catalystActivity[CatalystActivity:9632183] protein methyltransferase activity of PRMT1 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:9632180] Rothfels, Karen, 2018-12-14
input[SimpleEntity:5279190] AdoMet [cytoplasm]
[CandidateSet:9021065] PalmS-ESRs [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9021578] Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
[LiteratureReference:9632130] Regulation of estrogen rapid signaling through arginine methylation by PRMT1
[LiteratureReference:9022229] Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications
modified[InstanceEdit:9637801] Rothfels, Karen, 2019-02-19
[InstanceEdit:9637808] Rothfels, Karen, 2019-02-19
[InstanceEdit:9637945] Rothfels, Karen, 2019-02-21
[InstanceEdit:9645018] Rothfels, Karen, 2019-05-02
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePRMT1 methylates ESRs
output[SimpleEntity:71285] AdoHcy [cytosol]
[CandidateSet:9637789] Me-PalmS-ESRs [plasma membrane] [Homo sapiens]
precedingEvent
regulatedBy[PositiveRegulation:9632181] Positive regulation by 'ESTG [extracellular region]'
releaseDate2019-03-20
reviewed[InstanceEdit:9637806] Levin, Ellis R, 2019-02-19
[InstanceEdit:9645003] Acconcia, Filippo, 2019-04-24
[InstanceEdit:9645002] Marino, Maria, 2019-04-24
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9632184] R-HSA-9632182.3
summation[Summation:9632143] ESR1 is methylated by PRMT1 at arginine 260 in response to E...
(hasEvent)[Pathway:9009391] Extra-nuclear estrogen signaling [Homo sapiens]
(precedingEvent)[Reaction:9021170] Estrogen stimulates dimerization of plasma membrane estrogen receptors [Homo sapiens]
(updatedInstance)[_UpdateTracker:9777740] Update Tracker - [Reaction:9632182] PRMT1 methylates ESRs - v69:[addLiteratureReference, modifyText]
[Change default viewing format]
No pathways have been reviewed or authored by PRMT1 methylates ESRs (9632182)