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Details on Person UniProt:Q84UI5 MPK1
| Class:Id | ReferenceGeneProduct:9631627 |
|---|---|
| _chainChangeLog | chain:1-398 for 9631627 added on Fri February 15 2019 |
| _displayName | UniProt:Q84UI5 MPK1 |
| _timestamp | 2025-08-15 22:15:54 |
| chain | chain:1-398 |
| checksum | 46E2907463A7C490 |
| comment | FUNCTION Involved in sphingolipid elicitor (SE)-dependent defense signaling pathway. Acts downstream of heterotrimeric G protein alpha subunit and small GTPase RAC1. May regulate the expression of various genes involved in biotic and abiotic stress response (PubMed:15951489). Involved in an abscisic acid signaling pathway that regulates the activities of antioxidant enzymes and the production of hydrogen peroxide. Acts downstream of CCAMK (PubMed:23777258).CATALYTIC ACTIVITY L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)CATALYTIC ACTIVITY L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)ACTIVITY REGULATION Activated by threonine and tyrosine phosphorylation (By similarity). Activated in response to sphingolipid elicitor (SE).SUBUNIT May interact with RAC1.INDUCTION Induced by hydrogen peroxide and abscisic acid (ABA).DOMAIN The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.PTM Dually phosphorylated on Thr-225 and Tyr-227, which activates the enzyme.SIMILARITY Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. |
| created | [InstanceEdit:9631599] Gupta, Parul, 2018-12-10 |
| description | recommendedName: Mitogen-activated protein kinase 1 shortName: MAP kinase 1 ecNumber: 2.7.11.24 alternativeName: MAP kinase 6 alternativeName: OsMAPK6 alternativeName: OsSIPK |
| geneName | MPK1 MAPK6 SIPK Os06g0154500 LOC_Os06g06090 OSJNBa0085L11.14 |
| identifier | Q84UI5 |
| isSequenceChanged | FALSE |
| keyword | Abscisic acid signaling pathway ATP-binding Kinase Nucleotide-binding Phosphoprotein Plant defense Reference proteome Serine/threonine-protein kinase Transferase |
| modified | [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | MPK1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | MPK1_ORYSJ Q0DEG3 |
| sequenceLength | 398 |
| species | [Species:1250427] Oryza sativa subsp. japonica |
| (referenceEntity) | [EntityWithAccessionedSequence:9631658] MPK6 [nucleoplasm] [Oryza sativa] [EntityWithAccessionedSequence:9675391] MPK6 [nucleoplasm] [Oryza sativa] |
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No pathways have been reviewed or authored by UniProt:Q84UI5 MPK1 (9631627)
