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Details on Person Substrate translocates into late endosomal lumen

Class:Id	Reaction:9631065
_displayName	Substrate translocates into late endosomal lumen
_doRelease	TRUE
_timestamp	2019-11-12 10:03:56
authored	[InstanceEdit:9637871] Varusai, Thawfeek, 2019-02-21
compartment	[Compartment:172574] late endosome membrane [Compartment:173031] late endosome lumen [Compartment:70101] cytosol
created	[InstanceEdit:9631064] Varusai, Thawfeek, 2018-12-04
edited	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
inferredFrom	[Reaction:9631080] Substrate translocates into late endosomal lumen [Mus musculus]
input	[Complex:9631070] PL:HSPA8:Autophagy substrate [late endosome membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9631078] Microautophagy of cytosolic proteins by late endosomes
modified	[InstanceEdit:9631106] Varusai, Thawfeek, 2018-12-04 [InstanceEdit:9631180] Varusai, Thawfeek, 2018-12-05 [InstanceEdit:9631417] Varusai, Thawfeek, 2018-12-10 [InstanceEdit:9634153] Varusai, Thawfeek, 2019-01-07 [InstanceEdit:9637992] Varusai, Thawfeek, 2019-02-22 [InstanceEdit:9638325] Varusai, Thawfeek, 2019-03-05 [InstanceEdit:9667360] Varusai, Thawfeek, 2019-11-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Substrate translocates into late endosomal lumen
output	[Complex:9631107] PL:HSPA8:Autophagy substrate [late endosome lumen] [Homo sapiens]
precedingEvent	[Reaction:9631068] HSPA8:substrate binds late endosomal phospholipids [Homo sapiens] [Reaction:9615721] HSPA8 binds substrate [Homo sapiens]
regulatedBy	[PositiveRegulation:9631170] Positive regulation by 'ESCRT-I [endosome membrane]' [PositiveRegulation:9631181] Positive regulation by 'ESCRT-III [endosome membrane]'
releaseDate	2019-06-12
reviewed	[InstanceEdit:9637993] Metzakopian, Emmanouil, 2019-02-22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9631094] R-HSA-9631065.3
summation	[Summation:9631082] In addition to bulk protein degradation, Microautophagy (MI)...
(hasEvent)	[Pathway:9615710] Late endosomal microautophagy [Homo sapiens] [Pathway:9627221] HSPA8-mediated protein degradation [Homo sapiens]
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No pathways have been reviewed or authored by Substrate translocates into late endosomal lumen (9631065)