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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person p16INK4A V126D [cytosol]

Class:IdEntityWithAccessionedSequence:9631055
_displayNamep16INK4A V126D [cytosol]
_timestamp2019-05-06 20:25:07
compartment[Compartment:70101] cytosol
created[InstanceEdit:9631057] Orlic-Milacic, Marija, 2018-12-04
crossReference[DatabaseIdentifier:9631059] COSMIC:COSV58684293
[DatabaseIdentifier:9631058] COSMIC:COSM329718
disease[Disease:1614289] melanoma
[Disease:9630864] pancreatic ductal adenocarcinoma
[Disease:1500689] cancer
endCoordinate156
hasModifiedResidue[ReplacedResidue:9631056] L-valine 126 replaced with L-aspartic acid
literatureReference[LiteratureReference:9630871] Functional impairment of melanoma-associated p16(INK4a) mutants in melanoma cells despite retention of cyclin-dependent kinase 4 binding
[LiteratureReference:9631247] Functional reassessment of P16 variants using a transfection-based assay
modified[InstanceEdit:9631061] Orlic-Milacic, Marija, 2018-12-04
[InstanceEdit:9631062] Orlic-Milacic, Marija, 2018-12-04
[InstanceEdit:9631122] Orlic-Milacic, Marija, 2018-12-04
[InstanceEdit:9631332] Orlic-Milacic, Marija, 2018-12-06
[InstanceEdit:9645193] Orlic-Milacic, Marija, 2019-05-06
namep16INK4A V126D
p16INK4A Val126Asp
CDKN2A V126D
CDKN2A Val126Asp
referenceEntity[ReferenceGeneProduct:87039] UniProt:P42771 CDKN2A [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9631060] R-HSA-9631055.1
startCoordinate1
(hasMember)[CandidateSet:9630804] p16INK4A LoF mutants (CDK4/6) [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by p16INK4A V126D [cytosol] (9631055)