Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person p16INK4A G23D [cytosol]

Class:IdEntityWithAccessionedSequence:9630892
_displayNamep16INK4A G23D [cytosol]
_timestamp2019-05-06 20:11:49
compartment[Compartment:70101] cytosol
created[InstanceEdit:9630883] Orlic-Milacic, Marija, 2018-12-03
crossReference[DatabaseIdentifier:9630905] COSMIC:COSV58702991
[DatabaseIdentifier:9630906] COSMIC:COSM7339006
disease[Disease:1500689] cancer
[Disease:1614289] melanoma
[Disease:2327993] hepatocellular carcinoma
[Disease:1247848] non-small cell lung carcinoma
[Disease:2328083] larynx cancer
[Disease:9630864] pancreatic ductal adenocarcinoma
endCoordinate156
hasModifiedResidue[ReplacedResidue:9630889] glycine 23 replaced with L-aspartic acid
literatureReference[LiteratureReference:9630896] Functional impairment of p16(INK4A) due to CDKN2A p.Gly23Asp missense mutation
[LiteratureReference:9631144] CDKN2A unclassified variants in familial malignant melanoma: combining functional and computational approaches for their assessment
[LiteratureReference:9631273] Functional, structural, and genetic evaluation of 20 CDKN2A germ line mutations identified in melanoma-prone families or patients
[LiteratureReference:9631243] Predicting functional significance of cancer-associated p16(INK4a) mutations in CDKN2A
modified[InstanceEdit:9630907] Orlic-Milacic, Marija, 2018-12-03
[InstanceEdit:9631149] Orlic-Milacic, Marija, 2018-12-04
[InstanceEdit:9631324] Orlic-Milacic, Marija, 2018-12-06
[InstanceEdit:9645191] Orlic-Milacic, Marija, 2019-05-06
namep16INK4A G23D
p16INK4A Gly23Asp
CDKN2A G23D
CDKN2A Gly23Asp
referenceEntity[ReferenceGeneProduct:87039] UniProt:P42771 CDKN2A [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9630902] R-HSA-9630892.1
startCoordinate1
summation[Summation:9630898] p16INK4A G23D mutant is produced by a missense mutation in t...
(hasMember)[CandidateSet:9630826] p16INK4A LoF mutants (CDK4) [cytosol] [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by p16INK4A G23D [cytosol] (9630892)