Query author contributions in Reactome
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Details on Person Cyclic nucleotide phosphodiesterases (PDEs) are a large fami...
| Class:Id | Summation:9629667 |
|---|---|
| _displayName | Cyclic nucleotide phosphodiesterases (PDEs) are a large fami... |
| _timestamp | 2020-10-26 15:15:22 |
| created | [InstanceEdit:9629668] Jassal, Bijay, 2018-11-23 |
| modified | [InstanceEdit:9629688] Jassal, Bijay, 2018-11-23 [InstanceEdit:9705566] Jassal, Bijay, 2020-10-26 |
| text | Cyclic nucleotide phosphodiesterases (PDEs) are a large family of enzymes that regulate signal transduction by the second messenger molecules cAMP and cGMP (Maurice 2005). PDEs are important as drug targets:PDE3A inhibition promotes cardiac muscle contraction, a strategy used in heart failure. |
| (summation) | [Reaction:9629675] PDE3A hydrolyses cAMP to AMP [Homo sapiens] |
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No pathways have been reviewed or authored by Cyclic nucleotide phosphodiesterases (PDEs) are a large fami... (9629667)
