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Details on Person autoimmune hypersensitivity disease

Class:Id	Disease:9629266
_displayName	autoimmune hypersensitivity disease
_timestamp	2018-11-19 21:26:16
created	[InstanceEdit:9629269] Orlic-Milacic, Marija, 2018-11-19
definition	An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues.
identifier	417
name	autoimmune hypersensitivity disease
referenceDatabase	[ReferenceDatabase:1247631] DOID
synonym	autoimmune disease hypersensitivity reaction type II disease
(disease)	[Pathway:9629232] Defective Base Excision Repair Associated with NEIL3 [Homo sapiens] [FailedReaction:9629245] NEIL3 D132V does not cleave 5-guanidinohydantoin (Gh) [Homo sapiens] [Reaction:9824849] G or G analog binds C-ter TLR7 GoF variant [Homo sapiens] [Pathway:9824856] Defective regulation of TLR7 by endogenous ligand [Homo sapiens] [Complex:9629264] NEIL3 D132V:Gh-DNA [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9629268] NEIL3 D132V [nucleoplasm] [Homo sapiens] [ChemicalDrug:9678687] sirolimus [cytosol] [ChemicalDrug:9678991] tacrolimus [cytosol] [ProteinDrug:9681301] tocilizumab [extracellular region] [Complex:9824826] C-ter TLR7 Y264H dimer [endolysosome membrane] [Homo sapiens] List all 15 refering instances
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No pathways have been reviewed or authored by autoimmune hypersensitivity disease (9629266)