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Details on Person NEIL3 D132V does not cleave 5-guanidinohydantoin (Gh)

Class:IdFailedReaction:9629245
_displayNameNEIL3 D132V does not cleave 5-guanidinohydantoin (Gh)
_doReleaseTRUE
_timestamp2019-02-11 19:26:19
authored[InstanceEdit:9634075] Orlic-Milacic, Marija, 2019-01-04
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9629244] Orlic-Milacic, Marija, 2018-11-19
disease[Disease:9629266] autoimmune hypersensitivity disease
edited[InstanceEdit:9636025] Orlic-Milacic, Marija, 2019-02-11
entityFunctionalStatus[EntityFunctionalStatus:9629265] loss_of_function of NEIL3 D132V:Gh-DNA [nucleoplasm]
input[Complex:9629264] NEIL3 D132V:Gh-DNA [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9629236] Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity
modified[InstanceEdit:9629272] Orlic-Milacic, Marija, 2018-11-19
[InstanceEdit:9629972] Orlic-Milacic, Marija, 2018-11-26
[InstanceEdit:9635972] Orlic-Milacic, Marija, 2019-02-11
[InstanceEdit:9636025] Orlic-Milacic, Marija, 2019-02-11
[InstanceEdit:9636026] Orlic-Milacic, Marija, 2019-02-11
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNEIL3 D132V does not cleave 5-guanidinohydantoin (Gh)
normalReaction
releaseDate2019-03-20
reviewed[InstanceEdit:9635970] Zhou, Jia, 2019-02-11
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9629252] R-HSA-9629245.2
summation[Summation:9629231] NEIL3 D132V is a NEIL3 disease variant caused by a missense ...
(hasEvent)[Pathway:9629232] Defective Base Excision Repair Associated with NEIL3 [Homo sapiens]
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No pathways have been reviewed or authored by NEIL3 D132V does not cleave 5-guanidinohydantoin (Gh) (9629245)
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