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Details on Person SBH1:GET3:ADP:GET1:GET2 dissociates yielding SBH1 in the endoplasmic reticulum membrane

Class:Id	Reaction:9628640
_displayName	SBH1:GET3:ADP:GET1:GET2 dissociates yielding SBH1 in the endoplasmic reticulum membrane
_doRelease	TRUE
_timestamp	2018-11-25 04:06:45
authored	[InstanceEdit:9628624] May, Bruce, 2018-11-10
catalystActivity	[CatalystActivity:9628691] membrane insertase activity of SBH1:GET3:ADP:GET1:GET2 [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9628637] May, Bruce, 2018-11-10
edited	[InstanceEdit:9628624] May, Bruce, 2018-11-10
input	[Complex:9628642] SBH1:GET3:ADP:GET1:GET2 [endoplasmic reticulum membrane] [Saccharomyces cerevisiae] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9628645] Tail-Anchored Protein Insertion by a Single Get1/2 Heterodimer [LiteratureReference:9628384] The Get1/2 transmembrane complex is an endoplasmic-reticulum membrane protein insertase [LiteratureReference:9628659] The mechanism of tail-anchored protein insertion into the ER membrane [LiteratureReference:9628658] Get1 stabilizes an open dimer conformation of get3 ATPase by binding two distinct interfaces [LiteratureReference:9628656] The GET complex mediates insertion of tail-anchored proteins into the ER membrane [LiteratureReference:9629063] Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex
modified	[InstanceEdit:9628674] May, Bruce, 2018-11-10 [InstanceEdit:9628692] May, Bruce, 2018-11-11 [InstanceEdit:9628797] May, Bruce, 2018-11-13 [InstanceEdit:9629100] May, Bruce, 2018-11-19 [InstanceEdit:9629102] May, Bruce, 2018-11-19 [InstanceEdit:9629103] May, Bruce, 2018-11-19 [InstanceEdit:9629904] May, Bruce, 2018-11-25 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SBH1:GET3:ADP:GET1:GET2 dissociates yielding SBH1 in the endoplasmic reticulum membrane
output	[Complex:9628660] GET1:GET2 [endoplasmic reticulum membrane] [Saccharomyces cerevisiae] [Complex:9628625] GET3:ADP dimer [cytosol] [Saccharomyces cerevisiae] [EntityWithAccessionedSequence:9628639] SBH1 [endoplasmic reticulum membrane] [Saccharomyces cerevisiae] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
releaseDate	2019-03-20
reviewed	[InstanceEdit:9628231] DeLaurentiis, Evelina, 2018-11-07 [InstanceEdit:9628224] Farkas, �kos, 2018-11-07 [InstanceEdit:9628222] Schwappach, Blanche, 2018-11-07 [InstanceEdit:9629086] DeLaurentiis, Evelina, 2018-11-19
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:68322] Saccharomyces cerevisiae
stableIdentifier	[StableIdentifier:9628668] R-SCE-9628640.2
summation	[Summation:9628636] GET3:ADP docks with GET4:WDY2 (GET4:GET5), resulting in a co...
(inferredFrom)	[Reaction:9609917] Tail-anchored protein:ASNA1:ADP:WRB:CAMLG dissociates yielding Tail-anchored protein in the endoplasmic reticulum membrane [Homo sapiens]
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No pathways have been reviewed or authored by SBH1:GET3:ADP:GET1:GET2 dissociates yielding SBH1 in the endoplasmic reticulum membrane (9628640)