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Details on Person Expression of PLTP regulated by NR1H2 or NR1H3

Class:Id	BlackBoxEvent:9624365
_displayName	Expression of PLTP regulated by NR1H2 or NR1H3
_doRelease	TRUE
_timestamp	2019-08-12 15:22:04
authored	[InstanceEdit:9035107] Shamovsky, Veronica, 2018-01-18
compartment	[Compartment:7660] nucleoplasm [Compartment:984] extracellular region
created	[InstanceEdit:9624363] Shamovsky, Veronica, 2018-10-11
edited	[InstanceEdit:9657765] Shamovsky, Veronica, 2019-08-09
input	[EntityWithAccessionedSequence:9624350] PLTP gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9024440] Identification of PLTP as an LXR target gene and apoE as an FXR target gene reveals overlapping targets for the two nuclear receptors [LiteratureReference:9624358] The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions
modified	[InstanceEdit:9624568] Shamovsky, Veronica, 2018-10-12 [InstanceEdit:9634037] Shamovsky, Veronica, 2019-01-03 [InstanceEdit:9637777] Shamovsky, Veronica, 2019-02-19 [InstanceEdit:9657834] Shamovsky, Veronica, 2019-08-09 [InstanceEdit:9658282] Shamovsky, Veronica, 2019-08-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of PLTP regulated by NR1H2 or NR1H3
output	[CandidateSet:194227] PLTP [extracellular region] [Homo sapiens]
precedingEvent	[Reaction:9624353] NR1H2,3 binds the PLTP gene [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9624364] Positive gene expression regulation by 'NR1H2,3:RXR:NR1H2,3 ligand:PLTP gene [nucleoplasm]'
releaseDate	2019-09-10
reviewed	[InstanceEdit:9633727] D'Eustachio, Peter, 2018-12-29 [InstanceEdit:9657850] Cummins, Carolyn L, Repa, Joyce J, 2019-08-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9624366] R-HSA-9624365.2
summation	[Summation:9624362] The phospholipid transfer protein (PLTP) gene is transcribed...
(hasEvent)	[Pathway:9029569] NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux [Homo sapiens]
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No pathways have been reviewed or authored by Expression of PLTP regulated by NR1H2 or NR1H3 (9624365)