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Details on Person NR1H2,3 binds the PLTP gene

Class:IdReaction:9624353
_displayNameNR1H2,3 binds the PLTP gene
_doReleaseTRUE
_timestamp2019-08-12 15:59:25
authored[InstanceEdit:9035107] Shamovsky, Veronica, 2018-01-18
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9624348] Shamovsky, Veronica, 2018-10-11
edited[InstanceEdit:9657765] Shamovsky, Veronica, 2019-08-09
input[CandidateSet:9024381] NR1H2,3:RXR [nucleoplasm] [Homo sapiens]
[DefinedSet:9024383] NR1H3, NR1H2 ligands [nucleoplasm]
[EntityWithAccessionedSequence:9624350] PLTP gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9624358] The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions
[LiteratureReference:9024440] Identification of PLTP as an LXR target gene and apoE as an FXR target gene reveals overlapping targets for the two nuclear receptors
modified[InstanceEdit:9624568] Shamovsky, Veronica, 2018-10-12
[InstanceEdit:9634037] Shamovsky, Veronica, 2019-01-03
[InstanceEdit:9634161] Shamovsky, Veronica, 2019-01-07
[InstanceEdit:9637777] Shamovsky, Veronica, 2019-02-19
[InstanceEdit:9657834] Shamovsky, Veronica, 2019-08-09
[InstanceEdit:9658282] Shamovsky, Veronica, 2019-08-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNR1H2,3 binds the PLTP gene
LXR binds the PLTP gene
output[Complex:9624347] NR1H2,3:RXR:NR1H2,3 ligand:PLTP gene [nucleoplasm] [Homo sapiens]
releaseDate2019-09-10
reviewed[InstanceEdit:9633727] D'Eustachio, Peter, 2018-12-29
[InstanceEdit:9657850] Cummins, Carolyn L, Repa, Joyce J, 2019-08-09
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9624361] R-HSA-9624353.2
summation[Summation:9624357] Phospholipid transfer protein (PLTP) gene expression can be ...
(hasEvent)[Pathway:9029569] NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9624365] Expression of PLTP regulated by NR1H2 or NR1H3 [Homo sapiens]
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