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Details on Person p-SHC1 binds integrin alpha5beta1:fibronectin

Class:Id	Reaction:9624017
_displayName	p-SHC1 binds integrin alpha5beta1:fibronectin
_doRelease	TRUE
_timestamp	2021-11-12 13:10:45
authored	[InstanceEdit:9632125] Rothfels, Karen, 2018-12-14
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9624018] Rothfels, Karen, 2018-10-05
edited	[InstanceEdit:9758183] Rothfels, Karen, 2021-11-09
input	[CandidateSet:9623990] pY-SHC1 [cytosol] [Homo sapiens] [Complex:2327790] Integrin alpha5beta1:Fibronectin matrix [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9623941] Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor, GPR30 [LiteratureReference:9624251] Fibronectin fibrils and growth factors stimulate anchorage-independent growth of a murine mammary carcinoma [LiteratureReference:9624211] Cooperative effect of hepatocyte growth factor and fibronectin in anchorage-independent survival of mammary carcinoma cells: requirement for phosphatidylinositol 3-kinase activity [LiteratureReference:9624262] The G-protein-coupled estrogen receptor GPER in health and disease
modified	[InstanceEdit:9624282] Rothfels, Karen, 2018-10-09 [InstanceEdit:9637808] Rothfels, Karen, 2019-02-19 [InstanceEdit:9637951] Rothfels, Karen, 2019-02-21 [InstanceEdit:9754444] Rothfels, Karen, 2021-09-25 [InstanceEdit:9757292] Rothfels, Karen, 2021-10-28 [InstanceEdit:9758452] Rothfels, Karen, 2021-11-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-SHC1 binds integrin alpha5beta1:fibronectin
output	[Complex:9623993] integrin alpha5beta1:Fibronectin matrix:pY-SHC1 [plasma membrane] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9624014] SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 [Homo sapiens] [Reaction:9036308] ESTG-stimulated dissociation of GPER:heterotrimeric G-protein (s) complex [Homo sapiens]
releaseDate	2021-12-08
reviewed	[InstanceEdit:9645002] Marino, Maria, 2019-04-24 [InstanceEdit:9645003] Acconcia, Filippo, 2019-04-24
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9624019] R-HSA-9624017.2
summation	[Summation:9624007] Estradiol treatment of human breast cancer cells stimulates ...
(hasEvent)	[Pathway:9634597] GPER1 signaling [Homo sapiens]
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No pathways have been reviewed or authored by p-SHC1 binds integrin alpha5beta1:fibronectin (9624017)