Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person NR1H2,3 binds the MYLIP gene

Class:IdReaction:9623366
_displayNameNR1H2,3 binds the MYLIP gene
_doReleaseTRUE
_timestamp2019-08-12 15:59:03
authored[InstanceEdit:9035107] Shamovsky, Veronica, 2018-01-18
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9623369] Shamovsky, Veronica, 2018-10-04
input[CandidateSet:9024381] NR1H2,3:RXR [nucleoplasm] [Homo sapiens]
[DefinedSet:9024383] NR1H3, NR1H2 ligands [nucleoplasm]
[EntityWithAccessionedSequence:9623371] MYLIP gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:8854977] Feedback regulation of cholesterol uptake by the LXR-IDOL-LDLR axis
[LiteratureReference:8855264] LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
modified[InstanceEdit:9623380] Shamovsky, Veronica, 2018-10-04
[InstanceEdit:9624302] Shamovsky, Veronica, 2018-10-10
[InstanceEdit:9634037] Shamovsky, Veronica, 2019-01-03
[InstanceEdit:9634161] Shamovsky, Veronica, 2019-01-07
[InstanceEdit:9637777] Shamovsky, Veronica, 2019-02-19
[InstanceEdit:9657834] Shamovsky, Veronica, 2019-08-09
[InstanceEdit:9658282] Shamovsky, Veronica, 2019-08-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNR1H2,3 binds the MYLIP gene
LXR binds IDOL gene
output[Complex:9623370] NR1H2,3:RXR:NR1H2,3 ligand:MYLIP gene [nucleoplasm] [Homo sapiens]
releaseDate2019-09-10
reviewed[InstanceEdit:9633727] D'Eustachio, Peter, 2018-12-29
[InstanceEdit:9657850] Cummins, Carolyn L, Repa, Joyce J, 2019-08-09
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9623372] R-HSA-9623366.2
summation[Summation:9623364] Myosin regulatory light chain interacting protein (MYLIP, ak...
(hasEvent)[Pathway:9031525] NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9623365] Expression of MYLIP regulated by NR1H2,3 [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by NR1H2,3 binds the MYLIP gene (9623366)