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Details on Person ESR1-dependent CCND1 expression

Class:IdBlackBoxEvent:9623355
_displayNameESR1-dependent CCND1 expression
_doReleaseTRUE
_timestamp2019-02-21 22:07:57
authored[InstanceEdit:9632125] Rothfels, Karen, 2018-12-14
compartment[Compartment:7660] nucleoplasm
[Compartment:70101] cytosol
created[InstanceEdit:9623354] Rothfels, Karen, 2018-10-03
input[EntityWithAccessionedSequence:8853953] CCND1 gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9637967] Reduction in cyclin D1/Cdk4/retinoblastoma protein signaling by CRE-decoy oligonucleotide
[LiteratureReference:9637961] Estrogen-induced G1/S transition of G0-arrested estrogen-dependent breast cancer cells is regulated by mitochondrial oxidant signaling
modified[InstanceEdit:9632842] Rothfels, Karen, 2018-12-21
[InstanceEdit:9637808] Rothfels, Karen, 2019-02-19
[InstanceEdit:9637976] Rothfels, Karen, 2019-02-21
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameESR1-dependent CCND1 expression
output[EntityWithAccessionedSequence:68328] CCND1 [cytosol] [Homo sapiens]
precedingEvent
regulatedBy[PositiveGeneExpressionRegulation:9623347] Positive gene expression regulation by 'CCND1 gene:p-S133 CREB1 dimer [nucleoplasm]'
releaseDate2019-03-20
reviewed[InstanceEdit:9637806] Levin, Ellis R, 2019-02-19
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9623356] R-HSA-9623355.2
summation[Summation:9623353] Expression of CCND1, the gene encoding cyclin D1, is stimula...
(hasEvent)[Pathway:9634638] Estrogen-dependent nuclear events downstream of ESR-membrane signaling [Homo sapiens]
(precedingEvent)[Reaction:8941895] Formation of CDK4/6:CCND complexes [Homo sapiens]
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No pathways have been reviewed or authored by ESR1-dependent CCND1 expression (9623355)