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Details on Person Expression of CCND1, the gene encoding cyclin D1, is stimula...
| Class:Id | Summation:9623353 |
|---|---|
| _displayName | Expression of CCND1, the gene encoding cyclin D1, is stimula... |
| _timestamp | 2019-02-21 22:08:16 |
| created | [InstanceEdit:9623352] Rothfels, Karen, 2018-10-03 |
| modified | [InstanceEdit:9637978] Rothfels, Karen, 2019-02-21 |
| text | Expression of CCND1, the gene encoding cyclin D1, is stimulated by treatment of cells with E2. Expression is dependent on ESR1-mediated signaling through the PKA and AKT pathways, and consistent with this, levels of phosphorylated CREB1 increase upon treatment with E2. The CCND1 promoter has a CRE element that is bound by phosphorylated CREB1 upon E2 treatment as assessed by electrophoretic mobility shift assay (Park et al, 2001; Felty et al, 2005). |
| (summation) | [BlackBoxEvent:9623355] ESR1-dependent CCND1 expression [Homo sapiens] |
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No pathways have been reviewed or authored by Expression of CCND1, the gene encoding cyclin D1, is stimula... (9623353)
