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Details on Person p-S133 CREB1 dimer binds the CCND1 promoter

Class:IdReaction:9623341
_displayNamep-S133 CREB1 dimer binds the CCND1 promoter
_doReleaseTRUE
_timestamp2019-02-19 22:14:01
authored[InstanceEdit:9632125] Rothfels, Karen, 2018-12-14
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9623339] Rothfels, Karen, 2018-10-03
input[EntityWithAccessionedSequence:8853953] CCND1 gene [nucleoplasm] [Homo sapiens]
[Complex:111911] p-S133-CREB1 homodimer [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9623209] 17beta-estradiol inhibits oxidative stress-induced apoptosis in keratinocytes by promoting Bcl-2 expression
[LiteratureReference:9623301] 17beta-estradiol stimulates the growth of human keratinocytes by inducing cyclin D2 expression
[LiteratureReference:9623938] 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30
[LiteratureReference:9623987] The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells
[LiteratureReference:9623957] G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells
[LiteratureReference:9623943] Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells
[LiteratureReference:9623972] Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation
[LiteratureReference:9623979] The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells
[LiteratureReference:9622913] A role for G-protein coupled estrogen receptor (GPER) in estrogen-induced carcinogenesis: Dysregulated glandular homeostasis, survival and metastasis
[LiteratureReference:9632772] Cell proliferation regulated by estradiol receptor: Therapeutic implications
[LiteratureReference:9632114] PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells
[LiteratureReference:9632798] Role of atypical protein kinase C in estradiol-triggered G1/S progression of MCF-7 cells
[LiteratureReference:9632116] Tyrosine phosphorylation of estradiol receptor by Src regulates its hormone-dependent nuclear export and cell cycle progression in breast cancer cells
[LiteratureReference:9632788] Non-transcriptional action of oestradiol and progestin triggers DNA synthesis
modified[InstanceEdit:9624011] Rothfels, Karen, 2018-10-05
[InstanceEdit:9632847] Rothfels, Karen, 2018-12-21
[InstanceEdit:9637808] Rothfels, Karen, 2019-02-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namep-S133 CREB1 dimer binds the CCND1 promoter
output[Complex:9623342] CCND1 gene:p-S133 CREB1 dimer [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2019-03-20
reviewed[InstanceEdit:9637806] Levin, Ellis R, 2019-02-19
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9623344] R-HSA-9623341.2
summation[Summation:9623340] Estrogen stimulation promotes cell cycle progression in a nu...
(hasEvent)[Pathway:9634638] Estrogen-dependent nuclear events downstream of ESR-membrane signaling [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9623355] ESR1-dependent CCND1 expression [Homo sapiens]
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