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Details on Person Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF
| Class:Id | LiteratureReference:9622951 |
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| _displayName | Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF |
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| _timestamp | 2018-10-02 16:18:37 |
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| author | [Person:9622915] Filardo, Edward J
[Person:9622946] Quinn, Jeffrey A
[Person:9622949] Bland, Kirby I
[Person:9622953] Frackelton, A R |
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| created | [InstanceEdit:9622952] Rothfels, Karen, 2018-10-02 |
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| journal | Mol. Endocrinol. |
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| pages | 1649-60 |
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| pubMedIdentifier | 11043579 |
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| title | Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF |
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| volume | 14 |
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| year | 2000 |
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| (literatureReference) | [Reaction:9036307] GPER:Heterotrimeric G-protein Gs binds ESTG [Homo sapiens]
[Reaction:9036308] ESTG-stimulated dissociation of GPER:heterotrimeric G-protein (s) complex [Homo sapiens]
[BlackBoxEvent:9624014] SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 [Homo sapiens]
[Reaction:9625813] S1P binds S1PR3 in response to E2 stimulation [Homo sapiens]
[Reaction:9625814] SPHK1 phosphorylates sphingosine in response to E2 stimulation [Homo sapiens] |
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