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Details on Person microRNAs bind FOXO3 mRNA
Class:Id Reaction:9621429
_displayName microRNAs bind FOXO3 mRNA
_doRelease FALSE
_timestamp 2018-10-30 20:04:24
compartment [Compartment:70101] cytosol
created [InstanceEdit:9621430] Orlic-Milacic, Marija, 2018-09-26
inferredFrom
input [EntityWithAccessionedSequence:9621305] FOXO3 mRNA [cytosol] [Homo sapiens] [CandidateSet:9621445] miR-9,miR-132,miR-155,miR182,miR-212,miR-223 RISC,(miR-708 RISC) [cytosol] [Homo sapiens]
isChimeric FALSE
literatureReference [LiteratureReference:9621773] MicroRNA-155 increases colon cancer chemoresistance to cisplatin by targeting forkhead box O3 [LiteratureReference:9621719] miR-155, a Modulator of FOXO3a Protein Expression, Is Underexpressed and Cannot Be Upregulated by Stimulation of HOZOT, a Line of Multifunctional Treg [LiteratureReference:9621736] microRNA-155 regulates cell proliferation and invasion by targeting FOXO3a in glioma [LiteratureReference:9621746] MicroRNA-155 is involved in the pathogenesis of ulcerative colitis by targeting FOXO3a [LiteratureReference:9621762] MiR-155 is upregulated in patients with active tuberculosis and inhibits apoptosis of monocytes by targeting FOXO3 [LiteratureReference:9621795] MiR-155 is Involved in Renal Ischemia-Reperfusion Injury via Direct Targeting of FoxO3a and Regulating Renal Tubular Cell Pyroptosis [LiteratureReference:9621767] Paeonol protects against TNF-α-induced proliferation and cytokine release of rheumatoid arthritis fibroblast-like synoviocytes by upregulating FOXO3 through inhibition of miR-155 expression [LiteratureReference:9621806] MiR-155-5p promotes fibroblast cell proliferation and inhibits FOXO signaling pathway in vulvar lichen sclerosis by targeting FOXO3 and CDKN1B [LiteratureReference:9621832] A set of miRNAs that involve in the pathways of drug resistance and leukemic stem-cell differentiation is associated with the risk of relapse and glucocorticoid response in childhood ALL [LiteratureReference:9621868] Decoy oligonucleotide rescues IGF1R expression from MicroRNA-223 suppression [LiteratureReference:9621870] MicroRNA-223 Is Upregulated in Active Tuberculosis Patients and Inhibits Apoptosis of Macrophages by Targeting FOXO3 [LiteratureReference:9621850] MicroRNA-223 Promotes Type I Interferon Production in Antiviral Innate Immunity by Targeting Forkhead Box Protein O3 (FOXO3) [LiteratureReference:9621878] MicroRNA-132 and microRNA-223 control positive feedback circuit by regulating FOXO3a in inflammatory bowel disease [LiteratureReference:9621888] MicroRNA-223-3p regulates cell chemo-sensitivity by targeting FOXO3 in prostatic cancer [LiteratureReference:9621896] Effects of miR-223 on colorectal cancer cell proliferation and apoptosis through regulating FoxO3a/BIM [LiteratureReference:9621907] Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor [LiteratureReference:9621927] Sp1-mediated microRNA-182 expression regulates lung cancer progression [LiteratureReference:9621951] miR-182 attenuates atrophy-related gene expression by targeting FoxO3 in skeletal muscle [LiteratureReference:9621961] MicroRNA-182 inhibits HCMV replication through activation of type I IFN response by targeting FOXO3 in neural cells [LiteratureReference:9622144] Unregulated miR-96 induces cell proliferation in human breast cancer by downregulating transcriptional factor FOXO3a
modified [InstanceEdit:9621503] Orlic-Milacic, Marija, 2018-09-26 [InstanceEdit:9621546] Orlic-Milacic, Marija, 2018-09-26 [InstanceEdit:9621791] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9621793] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9621794] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9621803] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9621808] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9621842] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9621876] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9621886] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9621890] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9621898] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9621921] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9621936] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9621960] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9621968] Orlic-Milacic, Marija, 2018-09-27 [InstanceEdit:9622116] Orlic-Milacic, Marija, 2018-09-28 [InstanceEdit:9622149] Orlic-Milacic, Marija, 2018-09-28 [InstanceEdit:9626979] Orlic-Milacic, Marija, 2018-10-30
name microRNAs bind FOXO3 mRNA
output [Complex:9621541] FOXO3 mRNA:miR-9,miR-132,miR-155,miR-182,miR-212,miR-223,(miR-708) RISC [cytosol] [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9621450] R-HSA-9621429.1
summation [Summation:9621427] Based on studies in mice, miR-9 directly binds to the 3'UTR ...
(hasEvent) [Pathway:9614711] Regulation of FOXO expression [Homo sapiens]
(precedingEvent) [BlackBoxEvent:9621447] FOXO3 mRNA translation is inhibited by microRNAs [Homo sapiens]
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No pathways have been reviewed or authored by microRNAs bind FOXO3 mRNA (9621429)