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Details on Person EGR1 binds the VGF gene

Class:IdReaction:9620663
_displayNameEGR1 binds the VGF gene
_doReleaseTRUE
_timestamp2020-02-27 16:05:16
authored[InstanceEdit:9658548] Rothfels, Karen, 2019-08-16
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9620677] Rothfels, Karen, 2018-09-25
edited[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
inferredFrom
input[EntityWithAccessionedSequence:1031703] EGR1 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:9620667] VGF gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9620673] Nucleotide sequence and regulatory studies of VGF, a nervous system-specific mRNA that is rapidly and relatively selectively induced by nerve growth factor
[LiteratureReference:9620664] Structure of the gene encoding VGF, a nervous system-specific mRNA that is rapidly and selectively induced by nerve growth factor in PC12 cells
[LiteratureReference:9620674] Molecular cloning and characterization of the human VGF promoter region
[LiteratureReference:9620665] Regulatory elements in the promoter region of vgf, a nerve growth factor-inducible gene
[LiteratureReference:9620669] Interplay of the E box, the cyclic AMP response element, and HTF4/HEB in transcriptional regulation of the neurospecific, neurotrophin-inducible vgf gene
[LiteratureReference:9620658] Activation of codependent transcription factors is required for transcriptional induction of the vgf gene by nerve growth factor and Ras
[LiteratureReference:9031578] Global expression analysis identified a preferentially nerve growth factor-induced transcriptional program regulated by sustained mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) and AP-1 protein activation during PC12 cell differentiation
[LiteratureReference:9610764] Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells
modified[InstanceEdit:9664638] Rothfels, Karen, 2019-10-25
[InstanceEdit:9665683] Rothfels, Karen, 2019-10-31
[InstanceEdit:9674656] Rothfels, Karen, 2020-01-17
[InstanceEdit:9677119] Rothfels, Karen, 2020-02-27
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameEGR1 binds the VGF gene
output[Complex:9620670] VGF gene:EGR1 [nucleoplasm] [Homo sapiens]
releaseDate2020-03-17
reviewed[InstanceEdit:9674653] Aletta, John M, 2020-01-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9620681] R-HSA-9620663.2
summation[Summation:9620675] In neuronal cells, the VGF gene is induced by sustained NGF ...
(hasEvent)[Pathway:9031628] NGF-stimulated transcription [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9620723] VGF gene expression [Homo sapiens]
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No pathways have been reviewed or authored by EGR1 binds the VGF gene (9620663)
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