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Details on Person UniProt:Q810U3 Nfasc
Class:Id
ReferenceGeneProduct:96202
_chainChangeLog
signal peptide:1-24 added on Fri February 6 2015;chain:25-1240 added on Fri February 6 2015
_displayName
UniProt:Q810U3 Nfasc
_timestamp
2023-11-03 18:31:56
chain
signal peptide:1-24 chain:25-1240
checksum
6DE8935B5B02E965
comment
FUNCTION Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions.SUBUNIT Horseshoe-shaped homodimer. Probable constituent of a NFASC/NRCAM/ankyrin-G complex. Associates with the sodium channel beta-1 (SCN1B) and beta-3 (SCN3B) subunits. Interacts with GLDN/gliomedin (By similarity). Interacts with MYOC.SUBCELLULAR LOCATION Homophilic adhesion is primarily mediated by the interaction of the second Ig-like domains.SIMILARITY Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
description
recommendedName: Neurofascin
geneName
Nfasc
identifier
Q810U3
isSequenceChanged
FALSE
keyword
Cell adhesion Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix
