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Details on Person HSPA8:Substrate binds LAMP2a

Class:IdReaction:9620197
_displayNameHSPA8:Substrate binds LAMP2a
_doReleaseTRUE
_timestamp2019-11-12 09:58:26
authored[InstanceEdit:9637871] Varusai, Thawfeek, 2019-02-21
compartment[Compartment:17938] lysosomal membrane
[Compartment:70101] cytosol
created[InstanceEdit:9620198] Varusai, Thawfeek, 2018-09-21
edited[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
inferredFrom
input[Complex:9615717] HSPA8 bound autophagic substrates [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:2029007] LAMP2 [lysosomal membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9620201] A receptor for the selective uptake and degradation of proteins by lysosomes
[LiteratureReference:9620203] Unique properties of lamp2a compared to other lamp2 isoforms
modified[InstanceEdit:9620212] Varusai, Thawfeek, 2018-09-21
[InstanceEdit:9625192] Varusai, Thawfeek, 2018-10-19
[InstanceEdit:9626273] Varusai, Thawfeek, 2018-10-26
[InstanceEdit:9634155] Varusai, Thawfeek, 2019-01-07
[InstanceEdit:9637992] Varusai, Thawfeek, 2019-02-22
[InstanceEdit:9638325] Varusai, Thawfeek, 2019-03-05
[InstanceEdit:9667360] Varusai, Thawfeek, 2019-11-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameHSPA8:Substrate binds LAMP2a
output[Complex:9620204] HSPA8:Substrate:LAMP2a [lysosomal membrane] [Homo sapiens]
precedingEvent
releaseDate2019-06-12
reviewed[InstanceEdit:9637993] Metzakopian, Emmanouil, 2019-02-22
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9620210] R-HSA-9620197.3
summation[Summation:9620202] Intracellular proteins are targeted for proteolytic degradat...
(hasEvent)[Pathway:9613829] Chaperone Mediated Autophagy [Homo sapiens]
(precedingEvent)[Reaction:9622840] HSPA8 dissociates from LAMP2A-bound substrate [Homo sapiens]
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No pathways have been reviewed or authored by HSPA8:Substrate binds LAMP2a (9620197)