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Details on Person NR1H2 binds ABCA1

Class:IdReaction:9619756
_displayNameNR1H2 binds ABCA1
_doReleaseTRUE
_timestamp2019-08-12 15:25:05
authored[InstanceEdit:9035107] Shamovsky, Veronica, 2018-01-18
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:9619758] Shamovsky, Veronica, 2018-09-18
edited[InstanceEdit:9657765] Shamovsky, Veronica, 2019-08-09
input[EntityWithAccessionedSequence:194209] ABCA1 [plasma membrane] [Homo sapiens]
[Complex:9619754] NR1H2:RXRA [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9621107] Direct interaction of nuclear liver X receptor-beta with ABCA1 modulates cholesterol efflux
[LiteratureReference:9621108] Liver X receptor beta (LXRbeta) interacts directly with ATP-binding cassette A1 (ABCA1) to promote high density lipoprotein formation during acute cholesterol accumulation
modified[InstanceEdit:9623376] Shamovsky, Veronica, 2018-10-04
[InstanceEdit:9634037] Shamovsky, Veronica, 2019-01-03
[InstanceEdit:9637777] Shamovsky, Veronica, 2019-02-19
[InstanceEdit:9657834] Shamovsky, Veronica, 2019-08-09
[InstanceEdit:9658282] Shamovsky, Veronica, 2019-08-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNR1H2 binds ABCA1
LXR beta binds ABCA1
output[Complex:9619752] NR1H2:RXRA:ABCA1 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2019-09-10
reviewed[InstanceEdit:9633727] D'Eustachio, Peter, 2018-12-29
[InstanceEdit:9657850] Cummins, Carolyn L, Repa, Joyce J, 2019-08-09
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9619762] R-HSA-9619756.2
summation[Summation:9619759] In addition to its well defined role as a transcription fact...
(hasEvent)[Pathway:9029569] NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux [Homo sapiens]
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No pathways have been reviewed or authored by NR1H2 binds ABCA1 (9619756)