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Details on Person ACEIs translocate from ER lumen to extracellular region

Class:Id	BlackBoxEvent:9619034
_displayName	ACEIs translocate from ER lumen to extracellular region
_doRelease	TRUE
_timestamp	2018-09-14 14:20:46
authored	[InstanceEdit:9619045] Jassal, Bijay, 2018-09-14
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:984] extracellular region
created	[InstanceEdit:9619045] Jassal, Bijay, 2018-09-14
edited	[InstanceEdit:9619045] Jassal, Bijay, 2018-09-14
input	[DefinedSet:9619021] hydrolysed ACEIs [endoplasmic reticulum lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:9614927] Evaluation of angiotensin converting enzyme (ACE) in the pharmacokinetics and pharmacodynamics of ACE inhibitors
modified	[InstanceEdit:9619115] Jassal, Bijay, 2018-09-14 [InstanceEdit:9619116] Jassal, Bijay, 2018-09-14 [InstanceEdit:9619119] Jassal, Bijay, 2018-09-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ACEIs translocate from ER lumen to extracellular region
output	[DefinedSet:9619018] hydrolysed ACEIs [extracellular region]
precedingEvent	[Reaction:9619024] CES1 trimer hydrolyses ACEI pro-drugs to ACEIs [Homo sapiens]
releaseDate	2018-12-09
reviewed	[InstanceEdit:9619120] Toomey, John, 2018-09-14
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9619085] R-HSA-9619034.2
summation	[Summation:9619117] To exert their biological effects on extracellular angiotens...
(hasEvent)	[Pathway:2022377] Metabolism of Angiotensinogen to Angiotensins [Homo sapiens]
(precedingEvent)	[Reaction:9614933] ACEIs bind ACE [Homo sapiens]
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No pathways have been reviewed or authored by ACEIs translocate from ER lumen to extracellular region (9619034)