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Details on Person miR-26 binds to the 3'UTR of the ABCA1 mRNA

Class:Id	Reaction:9618486
_displayName	miR-26 binds to the 3'UTR of the ABCA1 mRNA
_doRelease	TRUE
_timestamp	2019-08-12 16:00:33
authored	[InstanceEdit:9035107] Shamovsky, Veronica, 2018-01-18
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9618484] Shamovsky, Veronica, 2018-09-07
edited	[InstanceEdit:9657765] Shamovsky, Veronica, 2019-08-09
input	[DefinedSet:9011867] miR-26 RISC [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9618483] ABCA1 mRNA [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9618471] MiR-26 controls LXR-dependent cholesterol efflux by targeting ABCA1 and ARL7
modified	[InstanceEdit:9634037] Shamovsky, Veronica, 2019-01-03 [InstanceEdit:9637777] Shamovsky, Veronica, 2019-02-19 [InstanceEdit:9657834] Shamovsky, Veronica, 2019-08-09 [InstanceEdit:9658282] Shamovsky, Veronica, 2019-08-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	miR-26 binds to the 3'UTR of the ABCA1 mRNA
output	[Complex:9618481] ABCA1 mRNA:miR-26 RISC [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9605057] ABCA1 gene transcription regulated by NR1H2 or NR1H3 [Homo sapiens] [Reaction:9024326] Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex [Homo sapiens]
releaseDate	2019-09-10
reviewed	[InstanceEdit:9633727] D'Eustachio, Peter, 2018-12-29 [InstanceEdit:9657850] Cummins, Carolyn L, Repa, Joyce J, 2019-08-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9618487] R-HSA-9618486.2
summation	[Summation:9618480] Micro RNA miR-26 was identified as a liver X receptor (LXR o...
(hasEvent)	[Pathway:9029569] NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9618479] ABCA1 mRNA is translated [Homo sapiens]
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No pathways have been reviewed or authored by miR-26 binds to the 3'UTR of the ABCA1 mRNA (9618486)