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Details on Person Rasgrf1 promotes activation of HRAS

Class:Id	Reaction:9617449
_displayName	Rasgrf1 promotes activation of HRAS
_doRelease	TRUE
_timestamp	2018-11-08 16:59:42
authored	[InstanceEdit:9624342] Orlic-Milacic, Marija, 2018-10-10
catalystActivity	[CatalystActivity:9617453] guanyl-nucleotide exchange factor activity of Rasgrf1 oligomer:CALM1:4xCa2+ [plasma membrane]
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9617451] Orlic-Milacic, Marija, 2018-08-27
edited	[InstanceEdit:9628239] Orlic-Milacic, Marija, 2018-11-07
input	[Complex:206896] HRAS:GDP [plasma membrane] [Homo sapiens] [SimpleEntity:29438] GTP [cytosol]
isChimeric	TRUE
literatureReference	[LiteratureReference:9617446] Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF
modified	[InstanceEdit:9617464] Orlic-Milacic, Marija, 2018-08-27 [InstanceEdit:9617465] Orlic-Milacic, Marija, 2018-08-27 [InstanceEdit:9628238] Orlic-Milacic, Marija, 2018-11-07 [InstanceEdit:9628240] Orlic-Milacic, Marija, 2018-11-07 [InstanceEdit:9628439] Orlic-Milacic, Marija, 2018-11-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Rasgrf1 promotes activation of HRAS
output	[Complex:206946] HRAS:GTP [plasma membrane] [Homo sapiens] [SimpleEntity:29420] GDP [cytosol]
releaseDate	2018-12-13
reviewed	[InstanceEdit:9627687] Yi, Feng, 2018-11-02 [InstanceEdit:9628437] Hansen, Kasper B, 2018-11-02
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48895] Rattus norvegicus [Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9617459] R-NUL-9617449.2
summation	[Summation:9617462] Recombinant rat Rasgrf1, expressed in human embryonic kidney...
(inferredFrom)	[Reaction:442732] NMDA-activated RASGRF1 activates RAS [Homo sapiens]
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No pathways have been reviewed or authored by Rasgrf1 promotes activation of HRAS (9617449)