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Details on Person Calm1:4xCa2+ binds GluN1:GluN2 (Grin1:Grin2) NMDA receptors and displaces Actn2

Class:IdReaction:9617322
_displayNameCalm1:4xCa2+ binds GluN1:GluN2 (Grin1:Grin2) NMDA receptors and displaces Actn2
_doReleaseTRUE
_timestamp2018-11-08 16:59:13
authored[InstanceEdit:9624342] Orlic-Milacic, Marija, 2018-10-10
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:9617328] Orlic-Milacic, Marija, 2018-08-22
edited[InstanceEdit:9628239] Orlic-Milacic, Marija, 2018-11-07
input[Complex:9617425] Calm1:4xCa2+ [cytosol] [Rattus norvegicus]
[Complex:9617423] Gly:L-Gly:Grin1:Grin2b NMDA receptors:Actn2:Dlg1:Dlg4:CaMKII [plasma membrane] [Rattus norvegicus]
isChimericFALSE
literatureReference[LiteratureReference:9611038] Competitive binding of alpha-actinin and calmodulin to the NMDA receptor
[LiteratureReference:9617321] Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit
modified[InstanceEdit:9617337] Orlic-Milacic, Marija, 2018-08-22
[InstanceEdit:9617434] Orlic-Milacic, Marija, 2018-08-27
[InstanceEdit:9628161] Orlic-Milacic, Marija, 2018-11-06
[InstanceEdit:9628236] Orlic-Milacic, Marija, 2018-11-07
[InstanceEdit:9628239] Orlic-Milacic, Marija, 2018-11-07
[InstanceEdit:9628240] Orlic-Milacic, Marija, 2018-11-07
[InstanceEdit:9628313] Orlic-Milacic, Marija, 2018-11-07
[InstanceEdit:9628439] Orlic-Milacic, Marija, 2018-11-08
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCalm1:4xCa2+ binds GluN1:GluN2 (Grin1:Grin2) NMDA receptors and displaces Actn2
output[Complex:9611048] Actn2 homodimer [cytosol] [Rattus norvegicus]
[Complex:9617424] Gly:L-Gly:Grin1:Grin2b NMDA receptors:Calm1:4xCa2+:Dlg1:Dlg4:CaMKII [plasma membrane] [Rattus norvegicus]
releaseDate2018-12-13
reviewed[InstanceEdit:9627687] Yi, Feng, 2018-11-02
[InstanceEdit:9628437] Hansen, Kasper B, 2018-11-02
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48895] Rattus norvegicus
stableIdentifier[StableIdentifier:9617331] R-RNO-9617322.2
summation[Summation:9617336] Based on studies in rat neurons, calmodulin (Calm1), activat...
(inferredFrom)[Reaction:9617326] CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 [Homo sapiens]
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No pathways have been reviewed or authored by Calm1:4xCa2+ binds GluN1:GluN2 (Grin1:Grin2) NMDA receptors and displaces Actn2 (9617322)