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Details on Person botA HC disulfide bonded [plasma membrane]

Class:Id	EntityWithAccessionedSequence:9616788
_displayName	botA HC disulfide bonded [plasma membrane]
_timestamp	2020-10-08 22:00:17
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9616789] D'Eustachio, Peter, 2018-08-14
disease	[Disease:3632909] botulism
endCoordinate	1296
goCellularComponent	[GO_CellularComponent:6485] host cell plasma membrane
hasModifiedResidue	[InterChainCrosslinkedResidue:5228587] Inter-chain Crosslink via L-cystine (cross-link) at 454 and 430
literatureReference	[LiteratureReference:5228581] Botulinum neurotoxin type A: cleavage of the heavy chain into two halves and their partial sequences [LiteratureReference:5228586] Partial amino acid sequence of the heavy and light chains of botulinum neurotoxin type A
modified	[InstanceEdit:9616791] D'Eustachio, Peter, 2018-08-14 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9704403] D'Eustachio, Peter, 2020-10-08 [InstanceEdit:9715688] Shorser, Solomon, 2021-02-17 [InstanceEdit:9729976] Shorser, Solomon, 2021-05-05 [InstanceEdit:9750461] Weiser, JD, 2021-08-11 [InstanceEdit:9757984] Weiser, JD, 2021-11-08 [InstanceEdit:9767390] Wright, Adam, 2022-02-25 [InstanceEdit:9773515] Weiser, Joel, 2022-05-04 [InstanceEdit:9909910] Weiser, Joel, 2024-05-14 [InstanceEdit:9917728] Weiser, Joel, 2024-08-09 [InstanceEdit:9926726] Weiser, Joel, 2024-11-03 [InstanceEdit:9939161] Weiser, Joel, 2025-02-21 [InstanceEdit:9948552] Weiser, Joel, 2025-05-21 [InstanceEdit:9963749] Weiser, Joel, 2025-08-15 [InstanceEdit:9970792] Weiser, Joel, 2025-10-31 [InstanceEdit:9983308] Weiser, Joel, 2026-02-22 [InstanceEdit:9989150] Weiser, Joel, 2026-05-15
name	botA HC disulfide bonded BoNT/A HC disulfide bonded BoNT Heavy chain Type A
referenceEntity	[ReferenceGeneProduct:9616775] UniProt:P0DPI0 botA [Clostridium botulinum]
species	[Species:168825] Clostridium botulinum
stableIdentifier	[StableIdentifier:9616790] R-CBO-9616788.20
startCoordinate	449
(hasComponent)	[Complex:5228948] botA HC:LC dimer [plasma membrane] [Clostridium botulinum]
(replacementInstances)	[_Deleted:9616792] Deletion of instance: 181496
(updatedInstance)	[_UpdateTracker:9901786] Update Tracker - [EntityWithAccessionedSequence:9616788] botA HC disulfide bonded [plasma membrane] - v75:[modifyName]
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No pathways have been reviewed or authored by botA HC disulfide bonded [plasma membrane] (9616788)