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Details on Person NAB2 binds EGR1 to repress CDK5R1 gene expression

Class:IdReaction:9616367
_displayNameNAB2 binds EGR1 to repress CDK5R1 gene expression
_doReleaseTRUE
_timestamp2020-02-27 16:05:50
authored[InstanceEdit:9658548] Rothfels, Karen, 2019-08-16
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9616372] Rothfels, Karen, 2018-08-10
edited[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
inferredFrom
input[Complex:9616091] CDK5R1 gene:EGR1 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:9612177] NAB2 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9612004] ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1
modified[InstanceEdit:9664638] Rothfels, Karen, 2019-10-25
[InstanceEdit:9665683] Rothfels, Karen, 2019-10-31
[InstanceEdit:9674656] Rothfels, Karen, 2020-01-17
[InstanceEdit:9677119] Rothfels, Karen, 2020-02-27
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNAB2 binds EGR1 to repress CDK5R1 gene expression
output[Complex:9616364] CDK5R1 gene:EGR1:NAB2 [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2020-03-17
reviewed[InstanceEdit:9674653] Aletta, John M, 2020-01-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9616379] R-HSA-9616367.2
summation[Summation:9616365] ERK- and EGR1-dependent expression of CDK5R1 is inhibited by...
(hasEvent)[Pathway:9031628] NGF-stimulated transcription [Homo sapiens]
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