Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person The evolutionarily conserved upstream enhancer of the Cebpa ...
| Class:Id | Summation:9616263 |
|---|---|
| _displayName | The evolutionarily conserved upstream enhancer of the Cebpa ... |
| _timestamp | 2019-01-09 22:22:05 |
| created | [InstanceEdit:9616266] May, Bruce, 2018-08-10 |
| modified | [InstanceEdit:9622436] May, Bruce, 2018-09-29 [InstanceEdit:9634378] May, Bruce, 2019-01-09 |
| text | The evolutionarily conserved upstream enhancer of the Cebpa gene binds Runx1 (Guo et al. 2012), Spi1 (PU.1), Gata2, Tal1 (Scl), Fli1, Myb, and Cebpa (Lane et al. 1996) in myeloid progenitor cells (Wilson et al. 2010, Guo et al. 2014, Cooper et al. 2015). Cebpa, Runx1, Gata2, SCL, SPI1, and Fli1 concomitantly bind the Cebpa promoter (Wilson et al. 2010, Cooper et al.2015). Runx1 appears to be required to produce sufficient Cebpa for granulopoiesis, as Cebpa:Cebpa homodimers favor granulopoiesis while monopoiesis is favored by a reduction in Runx1 (Guo et al. 2012) and AP-1:Cebpa heterodimers (Cooper et al. 2015). |
| (summation) | [Reaction:9616215] Runx1, Spi1, Gata2, Tal1, Fli1, Myb, and Cebpa bind the promoter of the Cebpa gene [Mus musculus] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The evolutionarily conserved upstream enhancer of the Cebpa ... (9616263)
