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Details on Person EGR1-dependent CDK5R1 gene expression

Class:Id	BlackBoxEvent:9616110
_displayName	EGR1-dependent CDK5R1 gene expression
_doRelease	TRUE
_timestamp	2020-02-27 16:05:27
authored	[InstanceEdit:9658548] Rothfels, Karen, 2019-08-16
compartment	[Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:9616109] Rothfels, Karen, 2018-08-09
edited	[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
input	[EntityWithAccessionedSequence:9616090] CDK5R1 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8862817] p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5 [LiteratureReference:9616058] A brain-specific activator of cyclin-dependent kinase 5 [LiteratureReference:9616039] The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation [LiteratureReference:9616047] Role of cyclins in neuronal differentiation of immortalized hippocampal cells [LiteratureReference:9616079] Evidence for the participation of the neuron-specific CDK5 activator P35 during laminin-enhanced axonal growth
modified	[InstanceEdit:9616381] Rothfels, Karen, 2018-08-10 [InstanceEdit:9664638] Rothfels, Karen, 2019-10-25 [InstanceEdit:9665683] Rothfels, Karen, 2019-10-31 [InstanceEdit:9674656] Rothfels, Karen, 2020-01-17 [InstanceEdit:9677119] Rothfels, Karen, 2020-02-27 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	EGR1-dependent CDK5R1 gene expression
output	[EntityWithAccessionedSequence:421083] MyrG-CDK5R1(2-307) [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:9616105] EGR1 binds CDK5R1 gene [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9616111] Positive gene expression regulation by 'CDK5R1 gene:EGR1 [nucleoplasm]' [NegativeGeneExpressionRegulation:9616366] Negative gene expression regulation by 'CDK5R1 gene:EGR1:NAB2 [nucleoplasm]'
releaseDate	2020-03-17
reviewed	[InstanceEdit:9674653] Aletta, John M, 2020-01-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9616112] R-HSA-9616110.2
summation	[Summation:9616088] CDK5R1 (also known as p35) is a neuron-specific regulator of...
(hasEvent)	[Pathway:9031628] NGF-stimulated transcription [Homo sapiens]
(precedingEvent)	[Reaction:9616368] MyrG-CDK5R1,2 bind CDK5 [Homo sapiens]
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No pathways have been reviewed or authored by EGR1-dependent CDK5R1 gene expression (9616110)