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Details on Person Latent Transcriptinally Repressed HCMV Genome

Class:Id	Reaction:9614816
_displayName	Latent Transcriptinally Repressed HCMV Genome
_doRelease	TRUE
_timestamp	2019-11-08 15:02:34
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9614813] Gillespie, Marc E, 2018-07-27
disease	[Disease:3134794] viral infectious disease
input	[EntityWithAccessionedSequence:9614372] Human herpesvirus 5 Genome - Merlin Strain [nucleoplasm] [Human cytomegalovirus] [Complex:4657034] Core histone octamer [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9653629] CBX1 [nucleoplasm] [Homo sapiens] [Complex:9653635] Daxx:PML [nucleoplasm] [Homo sapiens] [Complex:212285] PRC2 (EZH2) Core [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9614814] Chromatin structure regulates human cytomegalovirus gene expression during latency, reactivation and lytic infection [Book:9609668] Fields Virology 1451105630 Knipe, David Mahan Chapter 62 - Cytomegaloviruses [LiteratureReference:9653632] Human Cytomegalovirus Latency: Approaching the Gordian Knot [LiteratureReference:9653630] Cytomegalovirus latency and reactivation: recent insights into an age old problem [LiteratureReference:9653636] HCMV miRNA Targets Reveal Important Cellular Pathways for Viral Replication, Latency, and Reactivation
modified	[InstanceEdit:9614829] Gillespie, Marc E, 2018-07-27 [InstanceEdit:9653623] Gillespie, Marc E, 2019-07-12 [InstanceEdit:9653698] Gillespie, Marc E, 2019-07-12 [InstanceEdit:9653706] Gillespie, Marc E, 2019-07-12 [InstanceEdit:9663909] Gillespie, Marc E, 2019-10-18 [InstanceEdit:9667238] Gillespie, Marc E, 2019-11-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Latent Transcriptinally Repressed HCMV Genome
output	[Complex:9614812] Latent Transcriptionally Repressed HCMV Genome [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9614369] Transport of HCMV DNA Into the Nucleus [Homo sapiens] [Reaction:9614367] HCMV Nuclear Pore Docking [Homo sapiens]
regulatedBy	[Requirement:9653639] Requirement by 'HDAC3-containing complex [nucleoplasm]' [NegativeGeneExpressionRegulation:9653675] Negative gene expression regulation by 'UL133 [nucleoplasm]' [NegativeGeneExpressionRegulation:9653654] Negative gene expression regulation by 'UL138 [nucleoplasm]' [NegativeGeneExpressionRegulation:9653677] Negative gene expression regulation by 'UL111A [nucleoplasm]' [NegativeGeneExpressionRegulation:9653664] Negative gene expression regulation by 'US28 [nucleoplasm]' [NegativeGeneExpressionRegulation:9653676] Negative gene expression regulation by 'TRIM28 [nucleoplasm]' [NegativeGeneExpressionRegulation:9653703] Negative gene expression regulation by 'vRNA-2 [nucleoplasm]'
relatedSpecies	[Species:2671791] Human cytomegalovirus
releaseDate	2019-12-10
reviewed	[InstanceEdit:9663908] Caposio, Patrizia, Streblow, Daniel N, 2019-10-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9614817] R-HSA-9614816.2
summation	[Summation:9614828] Cells infected by with the Human Cytomegalovirus (HCMV) have...
(hasEvent)	[Pathway:9609690] HCMV Early Events [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9614810] Activation of Latent HCMV Genome [Homo sapiens]
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No pathways have been reviewed or authored by Latent Transcriptinally Repressed HCMV Genome (9614816)