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Details on Person FASLG gene expression is stimulated by FOXO1,FOXO3,(FOXO4)

Class:Id	BlackBoxEvent:9614669
_displayName	FASLG gene expression is stimulated by FOXO1,FOXO3,(FOXO4)
_doRelease	TRUE
_timestamp	2018-10-31 15:07:23
authored	[InstanceEdit:9624371] Orlic-Milacic, Marija, 2018-10-11
compartment	[Compartment:7660] nucleoplasm [Compartment:984] extracellular region
created	[InstanceEdit:9614670] Orlic-Milacic, Marija, 2018-07-27
edited	[InstanceEdit:9627016] Orlic-Milacic, Marija, 2018-10-31
input	[EntityWithAccessionedSequence:6797248] FASLG gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9614547] Inhibition of phosphorylation of a forkhead transcription factor sensitizes human ovarian cancer cells to cisplatin [LiteratureReference:199277] Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor [LiteratureReference:9614683] Inhibition of Akt kinase signalling and activation of Forkhead are indispensable for upregulation of FasL expression in apoptosis of glioma cells [LiteratureReference:9614691] miR-421 induces cell proliferation and apoptosis resistance in human nasopharyngeal carcinoma via downregulation of FOXO4 [LiteratureReference:9614698] microRNA-150 promotes cervical cancer cell growth and survival by targeting FOXO4
modified	[InstanceEdit:9614675] Orlic-Milacic, Marija, 2018-07-27 [InstanceEdit:9614678] Orlic-Milacic, Marija, 2018-07-27 [InstanceEdit:9614689] Orlic-Milacic, Marija, 2018-07-27 [InstanceEdit:9614700] Orlic-Milacic, Marija, 2018-07-27 [InstanceEdit:9623919] Orlic-Milacic, Marija, 2018-10-05 [InstanceEdit:9623920] Orlic-Milacic, Marija, 2018-10-05 [InstanceEdit:9625981] Orlic-Milacic, Marija, 2018-10-23 [InstanceEdit:9626979] Orlic-Milacic, Marija, 2018-10-30 [InstanceEdit:9626982] Orlic-Milacic, Marija, 2018-10-30 [InstanceEdit:9627002] Orlic-Milacic, Marija, 2018-10-31 [InstanceEdit:9627006] Orlic-Milacic, Marija, 2018-10-31 [InstanceEdit:9627017] Orlic-Milacic, Marija, 2018-10-31 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	FASLG gene expression is stimulated by FOXO1,FOXO3,(FOXO4)
output	[EntityWithAccessionedSequence:66212] FASLG(1-281) [extracellular region] [Homo sapiens]
precedingEvent	[Reaction:9614662] FOXO1,FOXO3,(FOXO4) bind FASLG gene promoter [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9614674] Positive gene expression regulation by 'FOXO1,FOXO3,(FOXO4):FASLG gene [nucleoplasm]'
releaseDate	2018-12-13
reviewed	[InstanceEdit:9625979] Donlon, Timothy, 2018-10-17 [InstanceEdit:9626974] Bertaggia, Enrico, 2018-10-26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9614671] R-HSA-9614669.2
summation	[Summation:9614676] Binding of FOXO1 (Ciechomska et al. 2003) or FOXO3 (Brunet e...
(hasEvent)	[Pathway:9614657] FOXO-mediated transcription of cell death genes [Homo sapiens]
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No pathways have been reviewed or authored by FASLG gene expression is stimulated by FOXO1,FOXO3,(FOXO4) (9614669)