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Details on Person Viral UL47:UL48 Proteins Bind HCMV Tegumented Virion to Host Microtuble and Dynein complexs

Class:Id	Reaction:9614343
_displayName	Viral UL47:UL48 Proteins Bind HCMV Tegumented Virion to Host Microtuble and Dynein complexs
_doRelease	TRUE
_timestamp	2019-11-08 15:02:37
authored	[InstanceEdit:9611824] Gillespie, Marc E, 2018-06-19
catalystActivity	[CatalystActivity:9614373] microtubule binding activity of HCMV Tegumented Virion [viral tegument]
catalystActivityReference	[CatalystActivityReference:9643267] microtubule binding activity of HCMV Tegumented Virion [viral tegument] Tegument proteins of human cytomegalovirus
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9614342] Gillespie, Marc E, 2018-07-24
disease	[Disease:3134794] viral infectious disease
goBiologicalProcess	[GO_BiologicalProcess:2454639] transport of viral material towards nucleus
input	[Complex:9606777] HCMV Tegumented Virion [viral tegument] [Human cytomegalovirus] [Complex:190599] Microtubule [cytosol] [Homo sapiens] [Complex:2029145] Dynein complex [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9614340] Microtubule network facilitates nuclear targeting of human cytomegalovirus capsid [Book:9609668] Fields Virology 1451105630 Knipe, David Mahan Chapter 62 - Cytomegaloviruses [LiteratureReference:9652664] Entry route of HCMV into endothelial cells
modified	[InstanceEdit:9614379] Gillespie, Marc E, 2018-07-24 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9652682] Gillespie, Marc E, 2019-07-02 [InstanceEdit:9653617] Gillespie, Marc E, 2019-07-11 [InstanceEdit:9663588] Gillespie, Marc E, 2019-10-04 [InstanceEdit:9663909] Gillespie, Marc E, 2019-10-18 [InstanceEdit:9667238] Gillespie, Marc E, 2019-11-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Viral UL47:UL48 Proteins Bind HCMV Tegumented Virion to Host Microtuble and Dynein complexs
output	[Complex:9614365] HCMV Tegmented Capsid:Dynein:Microtubule [cytoplasm] [Homo sapiens]
precedingEvent	[Reaction:9611147] Endocytic Uptake of HCMV Virion [Homo sapiens] [Reaction:9610867] HCMV Binds Host Cell Receptor - Endocytic Pathway [Homo sapiens] [Reaction:9611158] Fusion of HCMV Envelope with Plasma Membrane [Homo sapiens] [Reaction:9609689] HCMV Binds to the Host Cell via heparan sulfate proteoglycans (HSPG) [Homo sapiens]
relatedSpecies	[Species:2671791] Human cytomegalovirus
releaseDate	2019-12-10
reviewed	[InstanceEdit:9663908] Caposio, Patrizia, Streblow, Daniel N, 2019-10-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9614347] R-HSA-9614343.2
summation	[Summation:9614371] Tegument proteins help deliver the Human Cytomegalovirus (HC...
(hasEvent)	[Pathway:9609690] HCMV Early Events [Homo sapiens]
(precedingEvent)	[Reaction:9614367] HCMV Nuclear Pore Docking [Homo sapiens]
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No pathways have been reviewed or authored by Viral UL47:UL48 Proteins Bind HCMV Tegumented Virion to Host Microtuble and Dynein complexs (9614343)