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Details on Person SOX10 [nucleoplasm]
Class:Id EntityWithAccessionedSequence:9613639
_displayName SOX10 [nucleoplasm]
_timestamp 2018-07-16 19:51:47
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:9613640] Rothfels, Karen, 2018-07-16
endCoordinate 466
name SOX10 Transcription factor SOX-10 SOX10_HUMAN
referenceEntity [ReferenceGeneProduct:65320] UniProt:P56693 SOX10 [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9613642] R-HSA-9613639.1
startCoordinate 1
(activeUnit) [PositiveGeneExpressionRegulation:9613645] Positive gene expression regulation by 'POU3F1 gene:SOX10 dimer:HDAC2:SMARCA4 [nucleoplasm]' [PositiveGeneExpressionRegulation:9613762] Positive gene expression regulation by 'EGR2 gene:POU3F1:POU3F2:SOX10 [nucleoplasm]' [PositiveGeneExpressionRegulation:9614782] Positive gene expression regulation by 'MPZ gene:EGR2:SOX10:SMARCA4 [nucleoplasm]' [PositiveGeneExpressionRegulation:9615630] Positive gene expression regulation by 'MBP gene:EGR2:SOX10 [nucleoplasm]' [PositiveGeneExpressionRegulation:9616128] Positive gene expression regulation by 'MAG gene:EGR2:SOX10 [nucleoplasm]' [PositiveGeneExpressionRegulation:9618565] Positive gene expression regulation by 'PMP22 gene:EGR2:SOX10:TEAD1:WWTR1,YAP1 [nucleoplasm]' [PositiveGeneExpressionRegulation:9618736] Positive gene expression regulation by 'GJB11 gene:SOX10:EGR2:NAB1,2 [nucleoplasm]' [PositiveGeneExpressionRegulation:9619644] Positive gene expression regulation by 'PRX gene:EGR2:SOX10 [nucleoplasm]' [PositiveGeneExpressionRegulation:9730409] Positive gene expression regulation by 'SOX10:PAX3:MITF gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9774245] Positive gene expression regulation by 'SOX10:CDH19 gene [nucleoplasm]'
(hasComponent) [Complex:9613641] POU3F1 gene:SOX10 dimer:HDAC2:SMARCA4 [nucleoplasm] [Homo sapiens] [Complex:9613761] EGR2 gene:POU3F1:POU3F2:SOX10 [nucleoplasm] [Homo sapiens] [Complex:9614793] MPZ gene:EGR2:SOX10:SMARCA4 [nucleoplasm] [Homo sapiens] [Complex:9615629] MBP gene:EGR2:SOX10 [nucleoplasm] [Homo sapiens] [Complex:9616114] MAG gene:EGR2:SOX10 [nucleoplasm] [Homo sapiens] [Complex:9618555] PMP22 gene:EGR2:SOX10:TEAD1:WWTR1,YAP1 [nucleoplasm] [Homo sapiens] [Complex:9618726] GJB11 gene:SOX10:EGR2:NAB1,2 [nucleoplasm] [Homo sapiens] [Complex:9619633] PRX gene:EGR2:SOX10 [nucleoplasm] [Homo sapiens] [Complex:9730398] SOX10:PAX3:MITF gene [nucleoplasm] [Homo sapiens] [Complex:9774224] SOX10:CDH19 gene [nucleoplasm] [Homo sapiens]
(input) [Reaction:9613648] SOX10 dimer binds the POU3F1 promoter [Homo sapiens] [Reaction:9613768] SOX10, POU3F1 and POU3F2 bind EGR2 gene [Homo sapiens] [Reaction:9614790] EGR2, SOX10 and SMARCA4 bind the MPZ gene [Homo sapiens] [Reaction:9615638] EGR2 and SOX10 bind the MBP gene [Homo sapiens] [Reaction:9616116] EGR2 and SOX10 bind the MAG gene [Homo sapiens] [Reaction:9618559] EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene [Homo sapiens] [Reaction:9618725] SOX10, EGR2 and NAB proteins bind the GJB1 promoter [Homo sapiens] [Reaction:9619657] EGR2 and SOX10 bind the PRX gene [Homo sapiens] [Reaction:9730407] SOX10 and PAX3 bind the MITF promoter [Homo sapiens] [Reaction:9773192] SOX10 binds CDH19 gene promoter [Homo sapiens]
(marker) [MarkerReference:9730304] SOX10 [nucleoplasm] SOX10 mutations in patients with Waardenburg-Hirschsprung disease [MarkerReference:9907874] SOX10 [nucleoplasm] Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin
(proteinMarker) [Cell:9729103] migratory trunk neural crest cell [Homo sapiens] [Cell:9907771] Schwann cell precursor [Homo sapiens]
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Pathways
No pathways have been reviewed or authored by SOX10 [nucleoplasm] (9613639)