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Details on Person p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes

Class:Id	Reaction:9613451
_displayName	p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes
_doRelease	TRUE
_timestamp	2020-02-27 16:06:24
authored	[InstanceEdit:9658548] Rothfels, Karen, 2019-08-16
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9613450] Rothfels, Karen, 2018-07-13
edited	[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
input	[DefinedSet:9613449] ID1, ID3 gene [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:381325] EP300 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9613383] LYL1 [nucleoplasm] [Homo sapiens] [Complex:111911] p-S133-CREB1 homodimer [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9613604] Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions [LiteratureReference:9613614] Lyl1 interacts with CREB1 and alters expression of CREB1 target genes [LiteratureReference:9613447] The regulation and function of the Id proteins in lymphocyte development [LiteratureReference:9613405] ID1 and ID3 represent conserved negative regulators of human embryonic and induced pluripotent stem cell hematopoiesis [LiteratureReference:9613386] Combined Id1 and Id3 Deletion Leads to Severe Erythropoietic Disturbances
modified	[InstanceEdit:9613624] Rothfels, Karen, 2018-07-16 [InstanceEdit:9615430] Rothfels, Karen, 2018-08-03 [InstanceEdit:9664638] Rothfels, Karen, 2019-10-25 [InstanceEdit:9665683] Rothfels, Karen, 2019-10-31 [InstanceEdit:9674656] Rothfels, Karen, 2020-01-17 [InstanceEdit:9677119] Rothfels, Karen, 2020-02-27 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes
output	[Complex:9613448] ID1,ID3 genes:p-S133-CREB1:LYL1:EP300 [nucleoplasm] [Homo sapiens]
releaseDate	2020-03-17
reviewed	[InstanceEdit:9674653] Aletta, John M, 2020-01-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9613452] R-HSA-9613451.2
summation	[Summation:9613622] CREB1, EP300 and LYL1 are required for the activation of the...
(hasEvent)	[Pathway:9031628] NGF-stimulated transcription [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9613460] ID1 and ID3 gene expression [Homo sapiens]
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No pathways have been reviewed or authored by p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes (9613451)