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Details on Person RRAD gene expression

Class:Id	BlackBoxEvent:9613219
_displayName	RRAD gene expression
_doRelease	TRUE
_timestamp	2020-02-27 16:06:03
authored	[InstanceEdit:9658548] Rothfels, Karen, 2019-08-16
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9613218] Rothfels, Karen, 2018-07-11
edited	[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
input	[EntityWithAccessionedSequence:9613162] RRAD gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9613133] Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans [LiteratureReference:9613070] Characterization of Rad, a new member of Ras/GTPase superfamily, and its regulation by a unique GTPase-activating protein (GAP)-like activity [LiteratureReference:9613122] Rad GTPase deficiency leads to cardiac hypertrophy [LiteratureReference:9613126] Rad as a novel regulator of excitation-contraction coupling and beta-adrenergic signaling in heart [LiteratureReference:9613095] Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation [LiteratureReference:9613147] The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway [LiteratureReference:9613105] Neurotrophins regulate Schwann cell migration by activating divergent signaling pathways dependent on Rho GTPases [LiteratureReference:9613144] Rho kinase regulates schwann cell myelination and formation of associated axonal domains [LiteratureReference:9613138] Regulation of growth and tumorigenicity of breast cancer cells by the low molecular weight GTPase Rad and nm23 [LiteratureReference:9613077] EGR1 target genes in prostate carcinoma cells identified by microarray analysis [LiteratureReference:9613066] Active gene repression by the Egr2.NAB complex during peripheral nerve myelination [LiteratureReference:9613415] Local regulation of fat metabolism in peripheral nerves [LiteratureReference:9613395] Disruption of Krox20-Nab interaction in the mouse leads to peripheral neuropathy with biphasic evolution [LiteratureReference:9613103] Nab proteins are essential for peripheral nervous system myelination
modified	[InstanceEdit:9613480] Rothfels, Karen, 2018-07-13 [InstanceEdit:9664638] Rothfels, Karen, 2019-10-25 [InstanceEdit:9665683] Rothfels, Karen, 2019-10-31 [InstanceEdit:9674656] Rothfels, Karen, 2020-01-17 [InstanceEdit:9677119] Rothfels, Karen, 2020-02-27 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RRAD gene expression
output	[EntityWithAccessionedSequence:9613158] RRAD [cytosol] [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9613197] Positive gene expression regulation by 'RRAD gene:EGR1,EGR2 [nucleoplasm]' [NegativeGeneExpressionRegulation:9613192] Negative gene expression regulation by 'RRAD gene:EGR2:NAB2:CHD4 [nucleoplasm]'
releaseDate	2020-03-17
reviewed	[InstanceEdit:9674653] Aletta, John M, 2020-01-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9613220] R-HSA-9613219.2
summation	[Summation:9613216] RRAD (Ras associated with diabetes) is a small GTP-binding m...
(hasEvent)	[Pathway:9031628] NGF-stimulated transcription [Homo sapiens]
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No pathways have been reviewed or authored by RRAD gene expression (9613219)