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Details on Person ERBB4 can bind to a postsynaptic density (PSD) protein DLG4 ...
| Class:Id | Summation:9612576 |
|---|---|
| _displayName | ERBB4 can bind to a postsynaptic density (PSD) protein DLG4 ... |
| _timestamp | 2019-03-05 18:28:48 |
| created | [InstanceEdit:9612580] Orlic-Milacic, Marija, 2018-06-28 |
| literatureReference | [LiteratureReference:9612585] The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses [LiteratureReference:9612581] Regulation of neuregulin signaling by PSD-95 interacting with ErbB4 at CNS synapses [LiteratureReference:9612570] ErbB4 reduces synaptic GABAA currents independent of its receptor tyrosine kinase activity |
| modified | [InstanceEdit:9612882] Orlic-Milacic, Marija, 2018-06-29 [InstanceEdit:9638813] Orlic-Milacic, Marija, 2019-03-05 |
| text | ERBB4 can bind to a postsynaptic density (PSD) protein DLG4 (PSD-95) (Huang et al. 2000, Garcia et al. 2000). Binding to DLG4 enables ERBB4 to localize to the PSD, where it can modulate the activity of neurotransmitter receptors, but most ERBB4 receptors are found outside of the PSD in neuronal cells (Mitchell et al. 2013). One molecule of DLG4 can bind two molecules of ERBB4, which may facilitate ERBB4 dimerization upon ligand binding (Huang et al. 2000). |
| (summation) | [Reaction:9612593] ERBB4 binds DLG4 [Homo sapiens] |
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No pathways have been reviewed or authored by ERBB4 can bind to a postsynaptic density (PSD) protein DLG4 ... (9612576)
