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Details on Person NAB2 [nucleoplasm]

Class:Id	EntityWithAccessionedSequence:9612177
_displayName	NAB2 [nucleoplasm]
_timestamp	2023-10-31 23:23:59
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9612176] Rothfels, Karen, 2018-06-26
endCoordinate	525
modified	[InstanceEdit:9851828] D'Eustachio, Peter, 2023-10-31
name	NAB2 NGFI-A-binding protein 2 NAB2_HUMAN
referenceEntity	[ReferenceGeneProduct:59871] UniProt:Q15742 NAB2 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9612178] R-HSA-9612177.2
startCoordinate	1
(activeUnit)	[NegativeGeneExpressionRegulation:9613191] Negative gene expression regulation by 'EGR1 gene:EGR1:NAB1,NAB2 [nucleoplasm]' [NegativeGeneExpressionRegulation:9613192] Negative gene expression regulation by 'RRAD gene:EGR2:NAB2:CHD4 [nucleoplasm]' [NegativeRegulation:9613473] Negative regulation by 'ID2,ID4 gene:EGR2:NAB2:CHD4 [nucleoplasm]' [NegativeGeneExpressionRegulation:9616366] Negative gene expression regulation by 'CDK5R1 gene:EGR1:NAB2 [nucleoplasm]' [PositiveGeneExpressionRegulation:9618736] Positive gene expression regulation by 'GJB11 gene:SOX10:EGR2:NAB1,2 [nucleoplasm]'
(hasComponent)	[Complex:9613187] RRAD gene:EGR2:NAB2:CHD4 [nucleoplasm] [Homo sapiens] [Complex:9613463] ID2,ID4 gene:EGR2:NAB2:CHD4 [nucleoplasm] [Homo sapiens] [Complex:9616359] Cdk5r1 gene:Egr1:NAB2 [nucleoplasm] [Homo sapiens] [Complex:9616364] CDK5R1 gene:EGR1:NAB2 [nucleoplasm] [Homo sapiens]
(hasMember)	[DefinedSet:9612546] NAB1,2 [nucleoplasm] [Homo sapiens]
(input)	[Reaction:9613213] NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression [Homo sapiens] [Reaction:9613476] EGR2:NAB2 and CHD4 bind the ID2 and ID4 promoter regions [Homo sapiens] [Reaction:9616362] NAB2 binds Egr1 at the Cdk5r1 promoter [Homo sapiens] [Reaction:9616367] NAB2 binds EGR1 to repress CDK5R1 gene expression [Homo sapiens]
(output)	[BlackBoxEvent:9612493] EGR-dependent NAB2 gene expression [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9906518] Update Tracker - [EntityWithAccessionedSequence:9612177] NAB2 [nucleoplasm] - v87:[modifyEndCoordinate]
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No pathways have been reviewed or authored by NAB2 [nucleoplasm] (9612177)