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Details on Person HCMV Binds Host Cell Receptor - Endocytic Pathway
Class:Id Reaction:9610867
_displayName HCMV Binds Host Cell Receptor - Endocytic Pathway
_doRelease TRUE
_timestamp 2019-11-08 15:02:26
authored [InstanceEdit:9609684] Gillespie, Marc E, 2018-05-29
compartment [Compartment:984] extracellular region
created [InstanceEdit:9610870] Gillespie, Marc E, 2018-06-12
disease [Disease:3134794] viral infectious disease
input [SimpleEntity:1678620] HSPG [plasma membrane] [DefinedSet:9610864] HCMV Host Cell Receptors [plasma membrane] [Homo sapiens] [Complex:9609479] HCMV Mature Virion [extracellular region] [Human cytomegalovirus]
isChimeric FALSE
literatureReference [LiteratureReference:9610866] Heparan sulfate proteoglycans [Book:9609668] Fields Virology 1451105630 Knipe, David Mahan Chapter 62 - Cytomegaloviruses [LiteratureReference:9652664] Entry route of HCMV into endothelial cells [LiteratureReference:9652662] The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cells
modified [InstanceEdit:9652682] Gillespie, Marc E, 2019-07-02 [InstanceEdit:9663909] Gillespie, Marc E, 2019-10-18 [InstanceEdit:9667238] Gillespie, Marc E, 2019-11-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name HCMV Binds Host Cell Receptor - Endocytic Pathway
output [Complex:9609688] Enveloped HCMV Virion Bound to Entry Mediator [extracellular region] [Homo sapiens]
relatedSpecies [Species:2671791] Human cytomegalovirus
releaseDate 2019-12-10
reviewed [InstanceEdit:9663908] Caposio, Patrizia, Streblow, Daniel N, 2019-10-18
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9610874] R-HSA-9610867.2
summation [Summation:9610869] Viral attachment and penetration of Human Cytomegalovirus (H...
(hasEvent) [Pathway:9609690] HCMV Early Events [Homo sapiens]
(precedingEvent) [Reaction:9611147] Endocytic Uptake of HCMV Virion [Homo sapiens]
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