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Details on Person UniProt:A3A871 CYP71Z6

Class:IdReferenceGeneProduct:9610722
_displayNameUniProt:A3A871 CYP71Z6
_timestamp2025-08-15 22:16:31
chainchain:1-515
checksumB2AC8C84F25C073A
commentFUNCTION Enzyme of the diterpenoid metabolism involved in the biosynthesis of antibacterial oryzalides such as phytocassane.CATALYTIC ACTIVITY ent-isokaurene + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = ent-isokaurene-2beta,3beta-diol + 2 oxidized [NADPH--hemoprotein reductase] + 2 H2O + 2 H(+)COFACTOR kcat is 0.01 sec(-1) with ent-isokaurene as substrate.SUBCELLULAR LOCATION Belongs to the cytochrome P450 family.SEQUENCE CAUTION Truncated N-terminus.SEQUENCE CAUTION Truncated N-terminus.
created[InstanceEdit:9610732] Gupta, Parul, 2018-06-11
descriptionrecommendedName: Ent-isokaurene C2/C3-hydroxylase ecNumber evidence="3"1.14.14.76 alternativeName: Cytochrome P450 71Z6
geneNameCYP71Z6
Os02g0570500
LOC_Os02g36150
OsJ_07206
OSJNBa0008E01.28
identifierA3A871
isSequenceChangedFALSE
keywordHeme
Iron
Membrane
Metal-binding
Monooxygenase
NADP
Oxidoreductase
Reference proteome
Transmembrane
Transmembrane helix
modified[InstanceEdit:9616384] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9939033] Weiser, Joel, 2025-02-21
[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
nameCYP71Z6
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierC71Z6_ORYSJ
Q6YV92
sequenceLength515
species[Species:1250427] Oryza sativa subsp. japonica
(referenceEntity)[EntityWithAccessionedSequence:9610713] ent-isokaurene C2-hydroxylase [plastid membrane] [Oryza sativa]
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No pathways have been reviewed or authored by UniProt:A3A871 CYP71Z6 (9610722)