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Details on Person In mouse neurons, GluN1:GluN2B (Grin1:Grin2b) di-heteromers ...

Class:IdSummation:9610609
_displayNameIn mouse neurons, GluN1:GluN2B (Grin1:Grin2b) di-heteromers ...
_timestamp2019-02-12 19:28:03
created[InstanceEdit:9610610] Orlic-Milacic, Marija, 2018-06-11
modified[InstanceEdit:9636361] Orlic-Milacic, Marija, 2019-02-12
textIn mouse neurons, GluN1:GluN2B (Grin1:Grin2b) di-heteromers are transported to the plasma membrane from the endoplasmic reticulum (ER) via transport vesicles. At the membrane of transport vesicles, GluN1:GluN2b NMDA receptors associate with the complex of Lin7 (Lin7a, Lin7b or Lin7c), Cask and Apba1. The microtubule-associated kinesin motor protein Kif17 binds to the Lin7:Cask:Apba1 complex (Jo et al. 1999, Setou et al. 2000).
(summation)[Reaction:9610428] GluN1:GluN2B (Grin1:Grin2b) di-heterotetramers bind Lin7:Cask:Apba1 and Kif17 [Mus musculus]
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