Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Tail-anchored protein:ASNA1:ADP:WRB:CAMLG dissociates yielding Tail-anchored protein in the endoplasmic reticulum membrane

Class:Id	Reaction:9609917
_displayName	Tail-anchored protein:ASNA1:ADP:WRB:CAMLG dissociates yielding Tail-anchored protein in the endoplasmic reticulum membrane
_doRelease	TRUE
_timestamp	2018-11-25 04:08:04
authored	[InstanceEdit:9609862] May, Bruce, 2018-06-03
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9609858] May, Bruce, 2018-06-03
edited	[InstanceEdit:9609862] May, Bruce, 2018-06-03
inferredFrom	[Reaction:9628640] SBH1:GET3:ADP:GET1:GET2 dissociates yielding SBH1 in the endoplasmic reticulum membrane [Saccharomyces cerevisiae]
input	[Complex:9609912] Tail-anchored protein:ASNA1:ADP:WRB:CAMLG [endoplasmic reticulum membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:5250572] Identification of a targeting factor for posttranslational membrane protein insertion into the ER [LiteratureReference:5250588] Distinct targeting pathways for the membrane insertion of tail-anchored (TA) proteins [LiteratureReference:5250553] Asna1/TRC40-mediated membrane insertion of tail-anchored proteins [LiteratureReference:9613959] Molecular machinery for insertion of tail-anchored membrane proteins into the endoplasmic reticulum membrane in mammalian cells [LiteratureReference:9613944] WRB is the receptor for TRC40/Asna1-mediated insertion of tail-anchored proteins into the ER membrane [LiteratureReference:9613973] Tail-anchored Protein Insertion in Mammals: FUNCTION AND RECIPROCAL INTERACTIONS OF THE TWO SUBUNITS OF THE TRC40 RECEPTOR [LiteratureReference:9613989] Emery-Dreifuss muscular dystrophy mutations impair TRC40-mediated targeting of emerin to the inner nuclear membrane [LiteratureReference:9609907] Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing
modified	[InstanceEdit:9613982] May, Bruce, 2018-07-20 [InstanceEdit:9614003] May, Bruce, 2018-07-20 [InstanceEdit:9614006] May, Bruce, 2018-07-20 [InstanceEdit:9628235] May, Bruce, 2018-11-07 [InstanceEdit:9628513] May, Bruce, 2018-11-08 [InstanceEdit:9628514] May, Bruce, 2018-11-08 [InstanceEdit:9628672] May, Bruce, 2018-11-10 [InstanceEdit:9628797] May, Bruce, 2018-11-13 [InstanceEdit:9629100] May, Bruce, 2018-11-19 [InstanceEdit:9629102] May, Bruce, 2018-11-19 [InstanceEdit:9629103] May, Bruce, 2018-11-19 [InstanceEdit:9629904] May, Bruce, 2018-11-25 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Tail-anchored protein:ASNA1:ADP:WRB:CAMLG dissociates yielding Tail-anchored protein in the endoplasmic reticulum membrane
output	[DefinedSet:9609893] Tail-anchored proteins [endoplasmic reticulum membrane] [Homo sapiens] [Complex:9609864] WRB:CAMLG [endoplasmic reticulum membrane] [Homo sapiens] [Complex:9609895] ASNA1:ATP dimer [cytosol] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:9609899] Tail-anchored protein:ASNA1:ADP binds WRB:CAMLG at the endoplasmic reticulum membrane [Homo sapiens] [BlackBoxEvent:9609860] Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP dissociates and ASNA1 hydrolyzes ATP yielding Tail-anchored protein:ASNA1:ADP [Homo sapiens]
releaseDate	2019-03-20
reviewed	[InstanceEdit:9628231] DeLaurentiis, Evelina, 2018-11-07 [InstanceEdit:9628224] Farkas, �kos, 2018-11-07 [InstanceEdit:9628222] Schwappach, Blanche, 2018-11-07 [InstanceEdit:9629086] DeLaurentiis, Evelina, 2018-11-19
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9609954] R-HSA-9609917.2
summation	[Summation:9614005] A tail-anchored protein bound to ASNA1 (TRC40) (Stefanovic a...
(hasEvent)	[Pathway:9609523] Insertion of tail-anchored proteins into the endoplasmic reticulum membrane [Homo sapiens]
(replacementInstances)	[_Deleted:9629903] Deletion of instance: 5250579
[Change default viewing format]

No pathways have been reviewed or authored by Tail-anchored protein:ASNA1:ADP:WRB:CAMLG dissociates yielding Tail-anchored protein in the endoplasmic reticulum membrane (9609917)