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Query author contributions in Reactome

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Details on Person Active FLT3:GRB2 binds GAB2

Class:IdReaction:9606624
_displayNameActive FLT3:GRB2 binds GAB2
_doReleaseTRUE
_timestamp2019-05-21 08:34:49
authored[InstanceEdit:9634693] Varusai, Thawfeek, 2019-01-14
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:9606626] Varusai, Thawfeek, 2018-04-24
edited[InstanceEdit:9634693] Varusai, Thawfeek, 2019-01-14
inferredFrom
input[Complex:9604756] Active FLT3: GRB2 [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:508239] GAB2 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:6786770] Flt3 ligand induces tyrosine phosphorylation of gab1 and gab2 and their association with shp-2, grb2, and PI3 kinase
[LiteratureReference:9604764] A role of Gab2 association in Flt3 ITD mediated Stat5 phosphorylation and cell survival
[LiteratureReference:9604770] Direct binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3
modified[InstanceEdit:9606641] Varusai, Thawfeek, 2018-04-24
[InstanceEdit:9607241] Varusai, Thawfeek, 2018-05-01
[InstanceEdit:9607299] Varusai, Thawfeek, 2018-05-02
[InstanceEdit:9634820] Varusai, Thawfeek, 2019-01-16
[InstanceEdit:9645140] Varusai, Thawfeek, 2019-05-04
[InstanceEdit:9646277] Varusai, Thawfeek, 2019-05-21
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameActive FLT3:GRB2 binds GAB2
output[Complex:9606619] Active FLT3:GRB2:GAB2 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2019-06-12
reviewed[InstanceEdit:9645124] Traer, Elie, 2019-05-03
[InstanceEdit:9646275] Joshi, Sunil, 2019-05-21
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9606639] R-HSA-9606624.3
summation[Summation:9606620] Feline McDonough Sarcoma-like tyrosine kinase (FLT3) is a me...
(hasEvent)[Pathway:9607240] FLT3 Signaling [Homo sapiens]
(normalReaction)[Reaction:9698000] FLT3 mutants:GRB2 bind GAB2 [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9606622] GAB2 in Active FLT3:GRB2:GAB2 is phosphorylated [Homo sapiens]
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