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Details on Person MUTYH-3 R171W [nucleoplasm]

Class:Id	EntityWithAccessionedSequence:9606565
_displayName	MUTYH-3 R171W [nucleoplasm]
_timestamp	2018-04-24 18:04:44
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9606566] Orlic-Milacic, Marija, 2018-04-23
disease	[Disease:9605309] familial adenomatous polyposis [Disease:4791250] colorectal cancer
endCoordinate	535
hasModifiedResidue	[ReplacedResidue:9606567] L-arginine 171 replaced with L-tryptophan
literatureReference	[LiteratureReference:9606605] Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis [LiteratureReference:9606564] MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay
modified	[InstanceEdit:9606607] Orlic-Milacic, Marija, 2018-04-24 [InstanceEdit:9606667] Orlic-Milacic, Marija, 2018-04-24
name	MUTYH-3 R171W MUTYH-3 Arg171Trp MUTYH alpha-3 R171W MUTYH alpha-3 Arg171Trp
referenceEntity	[ReferenceIsoform:150746] UniProt:Q9UIF7-3 MUTYH [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9606575] R-HSA-9606565.1
startCoordinate	1
(hasMember)	[CandidateSet:9605329] MUTYH LOF mutants [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by MUTYH-3 R171W [nucleoplasm] (9606565)