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Details on Person MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay

Class:Id	LiteratureReference:9606564
_displayName	MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay
_timestamp	2018-04-23 18:23:10
author	[Person:9606574] Molatore, Sara [Person:9606568] Russo, Maria Teresa [Person:9606569] D'Agostino, Vito G [Person:9606573] Barone, Flavia [Person:5637504] Matsumoto, Yoshihiro [Person:9606572] Albertini, Alessandra M [Person:9606570] Minoprio, Anna [Person:5633098] Degan, Paolo [Person:9605486] Mazzei, Filomena [Person:9605489] Bignami, Margherita [Person:9606571] Ranzani, Guglielmina Nadia
created	[InstanceEdit:9606566] Orlic-Milacic, Marija, 2018-04-23
journal	Hum. Mutat.
pages	159-66
pubMedIdentifier	19953527
title	MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay
volume	31
year	2010
(literatureReference)	[FailedReaction:9605313] Defective MUTYH mutants do not cleave adenine mispaired with 8-oxoguanine [Homo sapiens] [Pathway:9608287] Defective MUTYH substrate binding [Homo sapiens] [FailedReaction:9608288] Defective MUTYH mutants do not bind adenine mispaired with 8-oxoguanine [Homo sapiens] [Pathway:9608290] Defective MUTYH substrate processing [Homo sapiens] [EntityWithAccessionedSequence:9605325] MUTYH-3 G382D [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9605328] MUTYH-3 Y165C [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9606565] MUTYH-3 R171W [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9606593] MUTYH-3 E466del [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9606594] MUTYH-3 W138_M139insIW [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay (9606564)