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Details on Person HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligand translocates to the nucleus

Class:IdBlackBoxEvent:9605352
_displayNameHSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligand translocates to the nucleus
_doReleaseFALSE
_timestamp2018-04-09 20:19:39
compartment[Compartment:70101] cytosol
[Compartment:13231] nuclear envelope
[Compartment:7660] nucleoplasm
created[InstanceEdit:9605349] Shamovsky, Veronica, 2018-04-09
edited[InstanceEdit:8979349] Shamovsky, Veronica, 2017-02-24
input[Complex:9605347] HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligand [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:8944764] FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells
nameHSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligand translocates to the nucleus
output[Complex:9605355] HSP90:ATP:PTGES3:FKBP52:NR3C1:NR3C1 ligand [nucleoplasm] [Homo sapiens]
precedingEvent
requiredInputComponent[Complex:157689] Nuclear Pore Complex (NPC) [nuclear envelope] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9605370] R-HSA-9605352.1
summation[Summation:9035352] Mineralocorticoid receptor (MR or NR3C2) is a ligand-induced...
(hasEvent)[Pathway:9605350] NR3C1-mediated signaling [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9605360] NR3C1 dissociates from HSP90 complex by ATP-dependent hydrolysis [Homo sapiens]
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